Results 11 to 20 of about 100,485 (295)

VacQuant: a tool to quantify neurodegeneration and associated vacuolation in brain tissue [PDF]

open access: yesFly
Neurodegenerative diseases are devastating conditions characterized by progressive cognitive decline with few available treatments. Neurodegeneration can be quantified in vertebrate and invertebrate models of disease by analysis of vacuolation – the ...
Kate L. Jordan   +3 more
doaj   +2 more sources

The clues offered by SNAREs on the vacuoles of plants and animals [PDF]

open access: yesFrontiers in Plant Science
Vacuoles and lysosome-related organelles (LROs) are essential compartments in eukaryotic cells playing crucial roles in storage, degradation, signaling, and homeostasis.
Fabrizio Barozzi   +3 more
doaj   +2 more sources

A case of VEXAS syndrome (vacuoles, E1 enzyme, X-linked, autoinflammatory, somatic) with decreased oxidative stress levels after oral prednisone and tocilizumab treatment

open access: yesFrontiers in Medicine, 2022
VEXAS (vacuoles, E1 enzyme, X-linked, autoinflammatory, somatic) syndrome has recently been described as an autoinflammatory disease associated with severe adult-onset inflammatory manifestations.
Nagie Tozaki   +17 more
doaj   +1 more source

Sulforaphane alters the acidification of the yeast vacuole

open access: yesMicrobial Cell, 2020
Sulforaphane (SFN) is a compound [1-isothiocyanato-4-(methylsulfinyl)-butane] found in broccoli and other cruciferous vegetables that is currently of interest because of its potential as a chemopreventive and a chemotherapeutic drug.
Alexander Wilcox   +9 more
doaj   +1 more source

Anti-Schistosomal Activity of Cinnamic Acid Esters: Eugenyl and Thymyl Cinnamate Induce Cytoplasmic Vacuoles and Death in Schistosomula of Schistosoma mansoni

open access: yesMolecules, 2015
Bornyl caffeate (1) was previously isolated by us from Valeriana (V.) wallichii rhizomes and identified as an anti-leishmanial substance. Here, we screened a small compound library of synthesized derivatives 1–30 for activity against schistosomula of ...
Jan Glaser   +4 more
doaj   +1 more source

Channeling the vacuole [PDF]

open access: yesNature Reviews Microbiology, 2018
Two recent studies provide new insights into the architecture, molecular mechanisms and function of the Plasmodium translocon of exported proteins (PTEX) complex and the core PTEX protein EXP2.
openaire   +2 more sources

VEXAS Syndrome—Review

open access: yesGlobal Medical Genetics, 2023
VEXAS (vacuoles, E1 enzyme, X-linked, autoinflammatory, somatic) syndrome is a newly defined refractory adult-onset autoinflammatory syndrome caused by somatic mutations in the ubiquitin-like modifier-activating enzyme 1 (UBA1) gene in hematopoietic stem
Zhang Zhang, Dong Dong, Wang Wang
doaj   +1 more source

THE ROLE OF VACUOLES [PDF]

open access: yesNew Phytologist, 1987
SUMMARYMany plant cells are characterized by the presence of a vacuole (hypertrophied lysosome) occupying a large fraction of the protoplast. The possible benefits of the presence of the vacuole can be divided into those which are related merely to the increased volume of the protoplast, independent of the nature of the vacuolar contents, and those ...
openaire   +2 more sources

The influence of osmotic stress on the content of calcium ions in the red beet vacuoles and on the transport activity of tonoplast proton pumps [PDF]

open access: yesJournal of Stress Physiology & Biochemistry, 2012
The contents of calcium ions in the isolated vacuoles and in intact red beets under the conditions of dormancy and osmotic stress was determined. It is demonstrated that the content of calcium ions in the red beet vacuoles not exposed to osmotic stress ...
Ozolina N.V.   +6 more
doaj  

The Vacuolating Autotransporter Toxin (Vat) of Escherichia coli Causes Cell Cytoskeleton Changes and Produces Non-lysosomal Vacuole Formation in Bladder Epithelial Cells

open access: yesFrontiers in Cellular and Infection Microbiology, 2020
Urinary tract infections (UTIs) affect more than 150 million people, with a cost of over 3.5 billion dollars, each year. Escherichia coli is associated with 70–80% of UTIs. Uropathogenic E.
Juan Manuel Díaz   +6 more
doaj   +1 more source

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