Results 21 to 30 of about 225,485 (404)

Pre-implantation mouse embryos cultured In vitro under different oxygen concentrations show altered ultrastructures [PDF]

, 2020
Assisted Reproductive Technologies routinely utilize different culture media and oxygen (O2) concentrations to culture human embryos. Overall, embryos cultured under physiological O2 tension (5%) have improved development compared to embryos cultured ...
Antonouli, S, Belli, M, Macchiarelli, G, Nottola, Sa, Palmerini, Mg, Rinaudo, P, Ruggeri, E   +6 more
core   +1 more source

VEXAS Syndrome—Review

Global Medical Genetics, 2023
VEXAS (vacuoles, E1 enzyme, X-linked, autoinflammatory, somatic) syndrome is a newly defined refractory adult-onset autoinflammatory syndrome caused by somatic mutations in the ubiquitin-like modifier-activating enzyme 1 (UBA1) gene in hematopoietic stem
Zhang Zhang, Dong Dong, Wang Wang
doaj   +1 more source

Ubiquitin, a central component of selective cytoplasmic proteolysis, is linked to proteins residing at the locus of non-selective proteolysis, the vacuole [PDF]

, 1992
Ubiquitin, an evolutionary highly conserved protein, is known to be involved in selective proteolysis in the cytoplasm. Here we show that ubiquitin-protein conjugates are also found in the yeast vacuole.
Achstetter, Angela Simeon, Dieter H. Wolf, Doherty, Fujiki, Gropper, Haas, Heinemeyer, Hershko, Hershko, Hershko, Heukeshoven, Ida J. van der Klei, Jones, Kato, Kornfeld, Laemmli, Lowry, Marten Veenhuis, Matile, Mechler, Meyer, Novick, Pennington, Roberts, Schwartz, Siegelman, Spormann, Steck, Teichert, Towbin, Tweto, van, Veenhuis, Wiemken, Yarden   +35 more
core   +6 more sources

Anti-Schistosomal Activity of Cinnamic Acid Esters: Eugenyl and Thymyl Cinnamate Induce Cytoplasmic Vacuoles and Death in Schistosomula of Schistosoma mansoni

Molecules, 2015
Bornyl caffeate (1) was previously isolated by us from Valeriana (V.) wallichii rhizomes and identified as an anti-leishmanial substance. Here, we screened a small compound library of synthesized derivatives 1–30 for activity against schistosomula of ...
Jan Glaser, Uta Schurigt, Brian M. Suzuki, Conor R. Caffrey, Ulrike Holzgrabe   +4 more
doaj   +1 more source

Photosynthesis dependent acidification of perialgal vacuoles in theParamedum bursaria/Chlorella symbiosis. Visualization by monensin [PDF]

, 1992
After treatment with the carboxylic ionophore monensin theChlorella containing perialgal vacuoles of the greenParamecium bursaria swell. TheParamecium cells remain motile at this concentration for at least one day.
A Fischer, AM Tartakoff, AM Tartakoff, B Matzke, BC Pressmann, DC Smith, E Cernichiari, E Kessler, H Kleinig, HH Mollenhauer, J Larsen, J Willenbrink, L Muscatine, MJ Geisow, N Stelly, R Sandeaux, TC Hohman, W Reisser, W Reisser, W Reisser, W Reisser, WF Boss   +21 more
core   +1 more source

Sulforaphane alters the acidification of the yeast vacuole

Microbial Cell, 2020
Sulforaphane (SFN) is a compound [1-isothiocyanato-4-(methylsulfinyl)-butane] found in broccoli and other cruciferous vegetables that is currently of interest because of its potential as a chemopreventive and a chemotherapeutic drug.
Alexander Wilcox, Michael Murphy, Douglass Tucker, David Laprade, Breton Roussel, Christopher Chin, Victoria Hallisey, Noah Kozub, Abraham Brass, Nicanor Austriaco   +9 more
doaj   +1 more source

IFNs Modify the Proteome of Legionella-Containing Vacuoles and Restrict Infection Via IRG1-Derived Itaconic Acid

PLoS Pathogens, 2016
Macrophages can be niches for bacterial pathogens or antibacterial effector cells depending on the pathogen and signals from the immune system. Here we show that type I and II IFNs are master regulators of gene expression during Legionella pneumophila ...
Jana Naujoks, C. Tabeling, B. D. Dill, C. Hoffmann, Andrew S. Brown, Mareike Kunze, S. Kempa, Andrea Peter, H. Mollenkopf, A. Dorhoi, O. Kershaw, A. Gruber, L. Sander, M. Witzenrath, S. Herold, A. Nerlich, A. Hocke, I. V. van Driel, N. Suttorp, S. Bedoui, H. Hilbi, M. Trost, B. Opitz   +22 more
semanticscholar   +1 more source

ATP-independent Control of Vac8 Palmitoylation by a SNARE Subcomplex on Yeast Vacuoles [PDF]

, 2005
Yeast vacuole fusion requires palmitoylated Vac8. We previously showed that Vac8 acylation occurs early in the fusion reaction, is blocked by antibodies against Sec18 (yeast N-ethylmaleimide-sensitive fusion protein (NSF)), and is mediated by the R-SNARE
Cristodero, Marina, Dietrich, Lars E. P., LaGrassa, Tracy J., Meiringer, Christoph T. A., Rohde, Jan, Ungermann, Christian   +5 more
core   +1 more source

A case of VEXAS syndrome (vacuoles, E1 enzyme, X-linked, autoinflammatory, somatic) with decreased oxidative stress levels after oral prednisone and tocilizumab treatment

Frontiers in Medicine, 2022
VEXAS (vacuoles, E1 enzyme, X-linked, autoinflammatory, somatic) syndrome has recently been described as an autoinflammatory disease associated with severe adult-onset inflammatory manifestations.
Nagie Tozaki, Chisato Tawada, Hirofumi Niwa, Yoko Mizutani, En Shu, Aki Kawase, Yuki Miwa, Hidenori Ohnishi, Hideo Sasai, Hideo Sasai, Keisuke Miyako, Junichi Hosokawa, Ayaka Kato, Kazuhiro Kobayashi, Tatsuhiko Miyazaki, Yohei Shirakami, Masahito Shimizu, Hiroaki Iwata   +17 more
doaj   +1 more source

Channeling the vacuole [PDF]

Nature Reviews Microbiology, 2018
Two recent studies provide new insights into the architecture, molecular mechanisms and function of the Plasmodium translocon of exported proteins (PTEX) complex and the core PTEX protein EXP2.
openaire   +2 more sources