Results 71 to 80 of about 2,665,933 (332)
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
THE STOCHASTIC APPROACHES OF PROCESSES’ DESIGN IN VACUUM-PLASMA FORMATION OF NANOSTRUCTURED COATINGS
Литьë и металлургия, 2017 The calculations of the spatial and energy parameters of a single-component metal plasma flow which is moved in a process gas environment using a numerical algorithm of test particle stochastic method are discussed.
I. A. Ivanou +2 more
doaj +1 more source
Molecular Oncology, EarlyView.Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang +3 more
wiley +1 more source
Probability distribution of the vacuum energy density
, 2010 As the vacuum state of a quantum field is not an eigenstate of the Hamiltonian density, the vacuum energy density can be represented as a random variable.
Duplancic, G., Glavan, D., Stefancic, H.
core +1 more source
Research on a Ka‐band large‐orbit gyro‐TWT with periodic dielectric‐loaded structure
Electronics LettersThis paper presents a design of a gyro‐TWT operating in the large‐orbit electron beam mode, with the aim of reducing the working magnetic field while ensuring operational efficiency.
Yang Jintao +6 more
doaj +1 more source
Journal of Aeronautical MaterialsSiOX/TPGDA/SiOX sandwiched films are fabricated by roll-to-roll plasma vapor deposition (roll-to-roll PECVD) and roll-to-roll evaporation coating technology.
FENG Erpeng +9 more
doaj +1 more source
Molecular Oncology, EarlyView.Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
Numerical simulation of the dolomite in-situ desulfurization in molten iron
Materials Research Express, 2023 With the growing need for high-quality steel, the requirement for efficient deep desulfurization technologies is growing, and lots of research have be conducted.
Shen Qiao-kun +4 more
doaj +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
, 2012 Birkhoff's theorem for spherically symmetric vacuum spacetimes is a key theorem in studying local systems in general relativity theory. However realistic local systems are only approximately spherically symmetric and only approximately vacuum.
A. Krasinski +9 more
core +1 more source