Results 71 to 80 of about 268,819 (187)

Maternal Prebiotic Supplementation Modifies Associations Between Intrapartum Antibiotics and Infant Allergy

Allergy, EarlyView.
This study examined whether antibiotic use altered the risk of infant allergic disease within a maternal prebiotics supplementation trial. Intrapartum antibiotics were maternal antibiotics administered during childbirth, from the onset of labour or induction until 1‐h before delivery.
Summer V. M. Walker, Thomas R. Sullivan, Rachelle A. Pretorius, Nina D'Vaz, Johnny Lo, Johan Garssen, Jeffrey A. Keelan, Desiree Silva, Susan L. Prescott, Claus T. Christophersen, Debra J. Palmer   +10 more
wiley   +1 more source

EVALUATING PREDICTIVE METABOLIC MODELLING TOOLS USING MICROBIOME SEQUENCING-METABOLOMIC DATA

, 2021
Metabolomic technologies have been utilized increasingly in tandem with sequencing technologies in microbiome studies. Combined microbiome-metabolome approaches have fueled the discovery of many convincing associations between disease-associated ...
Tang, Chris
core  

Post-coital dynamics of the penile and cervico-vaginal genital microbiome

Microbiome
Background The vaginal and penile coronal sulcus microbiome influence reproductive health outcomes and susceptibility to multiple sexually transmitted infections including HIV.
Daniel E. Park, Avid Mohammadi, Sydney G. Nelson, Juan E. Salazar, Sareh Bagherichimeh, Maliha Aziz, Abigail Onos, Jack Villani, Azadeh Fazel, Elizabeth Tevlin, Sanja Huibner, Wangari Tharao, Rupert Kaul, Cindy M. Liu   +13 more
doaj   +1 more source

Alterations of the paired maternal vaginal microbiome and neonatal meconium microbiome in vulvovaginal candidiasis positive pregnant women

Frontiers in Cellular and Infection Microbiology
BackgroundWomen with vulvovaginal candidiasis (VVC) are known to experience vaginal microbial dysbiosis. However, the dynamic alterations of the vaginal microbiome in pregnant women with VVC and its effect on neonatal gut microbiome remain unclear.
Hongqin Zhang, Hongping Li, Ruolin Zhang, Lingxia Ji, Jun Chen, Chuan Nie, Weimin Huang   +6 more
doaj   +1 more source

Association of Elevated C‐Reactive Protein in Term Newborns With Neonatal Factors and Gut Microbiota

Acta Paediatrica, EarlyView.
ABSTRACT Aim Plasma C‐reactive protein (CRP) is widely used to assess neonatal infection, although mild, unexplained elevations are common in healthy newborns. We examined relationships between non‐infectious CRP levels and neonatal factors, and early gut microbiota composition in term infants.
Susanna Gardemeister, Aki Saarikivi, Samuli Rautava, Jani Mälkönen, Willem M. de Vos, Katri Korpela, Kaija‐Leena Kolho   +6 more
wiley   +1 more source

Novel therapeutic targets for chronic visceral pain in gastrointestinal disorders

British Journal of Pharmacology, EarlyView.
Chronic visceral pain imposes a major clinical challenge in gastroenterology and beyond, profoundly impacting patients' quality of life. However, limited understanding of its complex, multifaceted pathophysiology, encompassing both peripheral and central mechanisms, continues to impede the development of effective management strategies.
Fleur Veldman, Christopher J. Black, Andrea Shin, Daniel Keszthelyi   +3 more
wiley   +1 more source

A guide to host genetic determinants of female microbiome composition across distinct anatomical niches

The FEBS Journal, EarlyView.
Host genetic variation in immune regulation and cell signalling genes was associated with microbiome composition across vaginal, gut, oral and skin sites, while associations involving metabolic function, epithelial barrier integrity and hormonal processes were more site‐specific. Overall, our findings indicate that host genetic variation contributes to
Isabella Margaret Davidson, Elham Nikbakht, Hayley O'Neill, Larisa Margaret Haupt, Paul Joseph Dunn   +4 more
wiley   +1 more source

Multinomial logistic regression of factors associated with having a vaginal microbiome dominated by different bacterial species.

, 2017
Multinomial logistic regression of factors associated with having a vaginal microbiome dominated by different bacterial species.
Jane S. Hocking (173696), Erica L. Plummer (3778513), Matthew G. Law (90623), Catriona S. Bradshaw (169624), Christopher K. Fairley (169632), Sepehr N. Tabrizi (169637), Katherine A. Fethers (663734), Jimmy Twin (169618), Suzanne M. Garland (169628), Eric P. F. Chow (115566), Lenka A. Vodstrcil (173720)   +10 more
core   +1 more source

Cationic Dendrimer G2-S16 Inhibits Herpes Simplex Type 2 Infection and Protects Mice Vaginal Microbiome

Pharmaceutics, 2020
The G2-S16 polyanionic carbosilane dendrimer is a promising microbicide that inhibits HSV-2 infection in vitro and in vivo in mice models. This G2-S16 dendrimer inhibits HSV-2 infection even in the presence of semen.
Carlos Guerrero-Beltrán, Inmaculada Garcia-Heredia, Rafael Ceña-Diez, Ignacio Rodriguez-Izquierdo, María Jesús Serramía, Francisco Martinez-Hernandez, Mónica Lluesma-Gomez, Manuel Martinez-Garcia, María Ángeles Muñoz-Fernández   +8 more
doaj   +1 more source

Female genital lichen sclerosus

Journal of the European Academy of Dermatology and Venereology, EarlyView.
This review provides a comprehensive overview of clinical presentation and emerging evidence supporting a predominantly immune‐mediated pathogenesis characterized by Th1‐skewed inflammation, epithelial dysfunction and progressive fibrosis. Contributory factors including the emerging role for occlusive exposure of susceptible epithelium to urine are ...
Ashley Spencer, Sandra Jerkovic Gulin
wiley   +1 more source