Results 51 to 60 of about 156,026 (273)

Vagus nerve stimulation inhibits cytokine production and attenuates disease severity in rheumatoid arthritis

Proceedings of the National Academy of Sciences of the United States of America, 2016
Significance Rheumatoid arthritis (RA) is a chronic, prevalent, and disabling autoimmune disease that occurs when inflammation damages joints. Recent advances in neuroscience and immunology have mapped neural circuits that regulate the onset and ...
F. Koopman, S. Chavan, S. Miljko, S. Grazio, S. Sokolovic, P. Schuurman, A. Mehta, Y. Levine, Michael A. Faltys, R. Zitnik, K. Tracey, P. Tak   +11 more
semanticscholar   +1 more source

Moving beyond belief: A narrative review of potential biomarkers for transcutaneous vagus nerve stimulation.

Psychophysiology, 2020
Transcutaneous vagus nerve stimulation (tVNS) is a non-invasive neurostimulation technique that is currently being tested as a potential treatment for a myriad of neurological and psychiatric disorders. However, the working mechanisms underlying tVNS are
A. Burger, Martina D’Agostini, B. Verkuil, I. Van Diest   +3 more
semanticscholar   +1 more source

A High-Frequency Flexible Ultrasonic Cuff Implant for High-Precision Vagus Nerve Ultrasound Neuromodulation [PDF]

arXiv, 2023
In the emerging research field of bioelectronic medicine, it has been indicated that neuromodulation of the Vagus Nerve (VN) has the potential to treat various conditions such as epilepsy, depression, and autoimmune diseases. In order to reduce side effects, as well as to increase the effectiveness of the delivered therapy, subfascicle stimulation ...
arxiv  

Stimulation parameters for directional vagus nerve stimulation

Bioelectronic Medicine, 2023
Abstract Background Autonomic nerve stimulation is used as a treatment for a growing number of diseases. We have previously demonstrated that application of efferent vagus nerve stimulation (eVNS) has promising glucose lowering effects in a rat model of type 2 diabetes.
Joel Villalobos, Sophie C. Payne, Glenn M. Ward, Sofianos Andrikopoulos, Tomoko Hyakumura, Richard J. MacIsaac, James B. Fallon   +6 more
openaire   +3 more sources

Short-pulsed micro-magnetic stimulation of the vagus nerve

Frontiers in Physiology, 2022
Vagus nerve stimulation (VNS) is commonly used to treat drug-resistant epilepsy and depression. The therapeutic effect of VNS depends on stimulating the afferent vagal fibers.
Hongbae Jeong, Annabel Cho, Annabel Cho, Ilknur Ay, Giorgio Bonmassar   +4 more
doaj   +1 more source

Functional vagotopy in the cervical vagus nerve of the domestic pig: implications for the study of vagus nerve stimulation

Journal of Neural Engineering, 2020
Objective. Given current clinical interest in vagus nerve stimulation (VNS), there are surprisingly few studies characterizing the anatomy of the vagus nerve in large animal models as it pertains to on-and off-target engagement of local fibers. We sought
Megan L. Settell, N. Pelot, Bruce E Knudsen, A. Dingle, A. McConico, Evan N. Nicolai, James K. Trevathan, J. A. Ezzell, Erika K. Ross, K. Gustafson, Andrew J. Shoffstall, Justin C. Williams, Weifeng Zeng, S. Poore, L. Populin, A. Suminski, W. Grill, K. Ludwig   +17 more
semanticscholar   +1 more source

Model-based geometrical optimisation and in vivo validation of a spatially selective multielectrode cuff array for vagus nerve neuromodulation [PDF]

, 2019
Background. Neuromodulation by electrical stimulation of the human cervical vagus nerve may be limited by adverse side effects due to stimulation of off-target organs. It may be possible to overcome this by spatially selective stimulation of peripheral nerves.
arxiv   +1 more source

Optical coherence tomography imaging of evoked neural activity in sciatic nerve of rat [PDF]

, 2020
Significance: Imaging neural activity in myelinated tissue using optical coherence tomography (OCT) creates new possibilities for functional imaging in the peripheral and central nervous systems. Aim: To investigate changes in OCT images in response to evoked neural activity in sciatic nerve of rat in vitro.
arxiv   +1 more source

Vagus nerve stimulation in cerebral stroke: biological mechanisms, therapeutic modalities, clinical applications, and future directions

Neural Regeneration Research
Stroke is a major disorder of the central nervous system that poses a serious threat to human life and quality of life. Many stroke victims are left with long-term neurological dysfunction, which adversely affects the well-being of the individual and the
Li Du, Xuan He, Xiaoxing Xiong, Xu Zhang, Zhihong Jian, Zhenxing Yang   +5 more
doaj   +1 more source

Mortality and suicide risk in treatment-resistant depression: an observational study of the long-term impact of intervention.

PLoS ONE, 2012
Major depressive disorder is a common global disease that causes a significant societal burden. Most interventional studies of depression provide a limited assessment of the interventions on mortality and suicide risks.
Bryan Olin, Amara K Jayewardene, Mark Bunker, Francisco Moreno   +3 more
doaj   +1 more source