Results 81 to 90 of about 45,261 (260)

Vagus nerve stimulation for the treatment of narcolepsy

Brain Stimulation
No study on neurostimulation in narcolepsy is available until now. Arousal- and wake-promoting effects of vagus nerve stimulation (VNS) have been demonstrated in animal experiments and are well-known as side effects of VNS therapy in epilepsy and depression. The objective was to evaluate the therapeutic effect of VNS on daily sleepiness and cataplexies
Yaroslav Winter, Katharina Sandner, Claudio L.A. Bassetti, Martin Glaser, Dumitru Ciolac, Andreas Ziebart, Ali Karakoyun, Assel Saryyeva, Joachim K. Krauss, Florian Ringel, Sergiu Groppa   +10 more
openaire   +4 more sources

Decreased homovanillic acid and 5‐hydroxyindoleacetic acid levels in the cerebrospinal fluid of patients with Dravet syndrome with parkinsonism

Epilepsia Open, EarlyView.
Abstract Dravet syndrome (DS) is an early onset, developmental, and epileptic encephalopathy characterized by drug‐resistant seizures and multiple comorbidities. It has been reported that in adulthood, it may be accompanied by parkinsonism, but the pathogenesis of this condition remains unclear.
Ryo Sugiyama, Takashi Saito, Atsuko Katsumoto, Shota Yoneno, Tomoyuki Akiyama, Hirofumi Komaki   +5 more
wiley   +1 more source

Effects of distention of the small intestine on the movements of the gallbladder and the sphincter of Oddi [PDF]

, 1969
1. Dogs anesthetized with pentobarbital sodium were mainly used and effects of the distention of the small intestine on the movements of the gall bladder and the sphincter of Oddi were investigated. 2.
Nakayama, Sosogu
core   +1 more source

Vagus nerve stimulation for epilepsy: a review

Seizure, 2000
Vagus nerve stimulation is an empirically based method for treatment of epilepsy by repeated stimulation of the left vagus nerve through implanted electrodes. Despite studies in animals and man, which show changes in brain electrophysiology, metabolism and neurochemistry, the mode of action remains unknown. Clinical testing has presented methodological
openaire   +3 more sources

Intestinal microbiome alterations in pediatric epilepsy: Implications for seizures and therapeutic approaches

Epilepsia Open, EarlyView.
Abstract The intestinal microbiome plays a pivotal role in maintaining host health through its involvement in gastrointestinal, immune, and central nervous system (CNS) functions. Recent evidence underscores the bidirectional communication between the microbiota, the gut, and the brain and the impact of this axis on neurological diseases, including ...
Teresa Ravizza, Greta Volpedo, Antonella Riva, Pasquale Striano, Annamaria Vezzani   +4 more
wiley   +1 more source

A pilot study on the programming protocol of vagus nerve stimulation in children with drug‐resistant epilepsy: High pulse amplitude or high duty cycle

Epilepsia Open, EarlyView.
Abstract Objective To compare the efficacy and safety of vagus nerve stimulation using different modes in patients with drug‐resistant epilepsy (DRE). Methods Children with DRE who underwent vagus nerve stimulator implantation between March 2019 and December 2022 were prospectively enrolled at the Peking University First Hospital.
Yuying Pan, Han Xie, Jiayi Ma, Taoyun Ji, Qingzhu Liu, Lixin Cai, Yuwu Jiang, Kai Zhang, Jianguo Zhang, Ye Wu   +9 more
wiley   +1 more source

Vagus Nerve Stimulation, Depression, and Inflammation [PDF]

Neuropsychopharmacology, 2007
Both acute and long-term studies suggested that vagus nerve stimulation (VNS) is of benefit in the therapy for treatment-resistant depression. VNS therapy acts via innervation of the nucleus tractus solitarius, with secondary projections to limbic and cortical structures that are involved in mood regulation, including brainstem regions that contain ...
openaire   +2 more sources

Efficacy of naloxone in reducing hypoxemia and duration of immobility following focal to bilateral tonic–clonic seizures

Epilepsia Open, EarlyView.
Abstract Objective Evaluating the efficacy of an opioid antagonist, naloxone (NLX), to reduce the severity of post‐ictal hypoxemia and immobility after focal to bilateral tonic–clonic seizures (FBTCS). Methods ENALEPSY is a double‐blind placebo (PCB)‐controlled trial conducted in patients with focal epilepsy undergoing long‐term video‐EEG monitoring ...
Sylvain Rheims, Fatima Chorfa, Véronique Michel, Edouard Hirsch, Louis Maillard, Luc Valton, Fabrice Bartolomei, Philippe Derambure, Vincent Navarro, Julien Biberon, Arielle Crespel, Anca Nica, Martine Lemesle Martin, Laure Mazzola, Jerome Petit, Vincent Rossero, Sébastien Boulogne, Mathilde Leclercq, Laurent Bezin, Catherine Mercier, Pascal Roy, Philippe Ryvlin, on behalf of the ENALEPSY Study Group, V. Michel, M. De Montaudouin, M. Lemesle Martin, P. Kahane, L. Minotti, L. Vercueil, A. S. Jobst, J. Petit, D. Tourniaire, V. Eid, P. Latour, P. Derambure, W. Szurhaj, S. Rheims, H. Catenoix, N. Andre‐Obadia, J. Isnard, A. Montavont, S. Boulogne, F. Bartolomei, A. Trébuchon, A. Mc Gonigal, S. Aubert, S. Lagarde, A. Crespel, P. Gelisse, B. Mercedes, L. Maillard, L. Tyvaert, J. P. Vignal, V. Navarro, S. Dupont, C. Adam, V. Frazzini, V.‐H. Nguyen‐Michel, M. Damiano, V. Lambrecq, A. Biraben, A. Nica, P. Convers, L. Mazzola, E. Hirsch, M. P. Valenti, J. Scholly, C. Behr, L. Valton, M. Denuelle, J. Curot, J. Biberon   +71 more
wiley   +1 more source

Building a dashboard to inform policy and clinical practice using the Irish epilepsy electronic patient record: Towards a learning health system

Epilepsia Open, EarlyView.
Abstract Objectives Ireland lags heavily in capacity and stakeholder interest for the development of learning health system tools. However, Ireland possesses a rich repository of electronic patient records for epilepsy patients stored at the National Epilepsy Centre at Beaumont Hospital.
Ian A. J. Darragh, Laura Brady, Norman Delanty, Colin Doherty, David Lewis‐Smith, Kathleen E. Bennett   +5 more
wiley   +1 more source

Regional epilepsy: Unraveling the epileptic phenomenon

Epileptic Disorders, EarlyView.
Shreyashish Roy‐Chowdhury, Elma Paredes‐Aragon, Richard S. McLachlan, Jorge G. Burneo, David A. Steven, Ana Suller Marti   +5 more
wiley   +1 more source