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Treatment of congenital cytomegalovirus infection [PDF]

Clinical and Experimental Pediatrics, 2023
Congenital cytomegalovirus (CMV) is the most common cause of congenital infection worldwide, the most common nongenetic cause of sensorineural hearing loss in children, and a cause of neurodevelopmental disorders in the brain.
Gyu Hong Shim
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Valganciclovir Inhibits Human Adenovirus Replication and Pathology in Permissive Immunosuppressed Female and Male Syrian Hamsters

Viruses, 2015
Adenovirus infections of immunocompromised pediatric hematopoietic stem cell transplant patients can develop into serious and often deadly multi-organ disease. There are no drugs approved for adenovirus infections.
Karoly Toth, Baoling Ying, Ann E. Tollefson, Jacqueline F. Spencer, Lata Balakrishnan, John E. Sagartz, Robert Mark L. Buller, William S. M. Wold   +7 more
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Valganciclovir as Add-On to Standard Therapy in Secondary Glioblastoma

Microorganisms, 2020
Patients with glioblastoma have a very poor prognosis despite aggressive therapeutic strategies. Cytomegalovirus has been detected in >90% of glioblastoma tumors.
Giuseppe Stragliotto, Mattia Russel Pantalone, Afsar Rahbar, Cecilia Söderberg-Nauclér   +3 more
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Chronic Human Herpes Virus 8 Infection Successfully Treated With Valganciclovir

World Allergy Organization Journal, 2009
Background: A 57 year old Italian female with a 3 year history of constituitional symptoms with non-HIV Kaposi sarcoma was referred to the immunology clinic.
James J. Yun, MBBS, Veronica Preda, MBBS(Hons), BSc(Med), Brad Frankum, BMed(Hons), FRACP   +2 more
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Treating HIV-associated cytomegalovirus retinitis with oral valganciclovir and intra-ocular ganciclovir by primary HIV clinicians in southern Myanmar: a retrospective analysis of routinely collected data

BMC Infectious Diseases, 2020
Background Cytomegalovirus retinitis (CMVR) is an opportunistic infection in HIV-infected people. Intraocular or intravenous ganciclovir was gold standard for treatment; however, oral valganciclovir replaced this in high-income countries. Low- and middle-
Jillian Murray, Adelene Hilbig, Theint Thida Soe, Win Le Shwe Sin Ei, Kyi Pyar Soe, Iza Ciglenecki   +5 more
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Oral Administration of Valganciclovir Reduces Clinical Signs, Virus Shedding and Cell-Associated Viremia in Ponies Experimentally Infected with the Equid Herpesvirus-1 C₂₂₅₄ Variant

Pathogens, 2022
Equid alphaherpesvirus-1 (EHV-1) is one of the main pathogens in horses, responsible for respiratory diseases, ocular diseases, abortions, neonatal foal death and neurological complications such as equine herpesvirus myeloencephalopathy (EHM).
Côme J. Thieulent, Gabrielle Sutton, Marie-Pierre Toquet, Samuel Fremaux, Erika Hue, Christine Fortier, Alexis Pléau, Alain Deslis, Stéphane Abrioux, Edouard Guitton, Stéphane Pronost, Romain Paillot   +11 more
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Optimising graft survival in endothelial keratoplasty for endothelial failure secondary to cytomegalovirus endotheliitis

Journal of Ophthalmic Inflammation and Infection, 2019
Background There is limited information regarding Descemet stripping automated endothelial keratoplasty (DSAEK) for endothelial failure secondary to cytomegalovirus (CMV) endotheliitis. Treatment is difficult with high recurrence rates.
Milton C. Chew, Donald T. Tan, Soon-Phaik Chee, Lim Li   +3 more
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Hearing loss in children with congenital cytomegalovirus infection

Revista Portuguesa Otorrinolaringologia e Cirurgia de Cabeça e Pescoço, 2023
Objective: To study the prevalence of hearing loss in children with congenital Cytomegalovirus infection and the influence of the type of maternal infection, symptoms and neonatal treatment with valganciclovir.
Gonçalo Caetano Oliveira, Filipa Morgado, Mariana Santos, Clara Mota, Ricardo Matos, Raquel Robles, Rui Fonseca   +6 more
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Congenital cytomegalovirus infection: features of the clinical course and catamnesis according to own observations

Журнал инфектологии, 2022
Congenital cytomegalovirus infection is the most common congenital infection, occurs in 0.6-5% of newborns worldwide, and is considered the leading non-genetic cause of sensorineural hearing loss in children.
E. V. Antsiferova, T. E. Taranushenko, D. G. Geninova, L. N. Karpova, L. A. Filippova, K. I. Karaganova, L. S. Karpova   +6 more
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Valganciclovir for cytomegalovirus preemptive therapy in patients following allogeneic hematopoietic stem cell transplantation

Di-san junyi daxue xuebao, 2020
Objective and;To evaluate the clinical value of valganciclovir in preemptive treatment of cytomegalovirus (CMV) infection after allogeneic hematopoietic stem cell transplantation (allo-HSCT) by comparing the efficacy of the drug with other conventional ...
LU Xuan, YAN Han, XIA Linghui
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