Results 11 to 20 of about 9,286 (149)

Human Cytomegalovirus Genetic Diversity, Clinical Relevance, and Emerging Insights. [PDF]

Rev Med Virol
ABSTRACT Human cytomegalovirus (HCMV) is a globally prevalent virus that poses a significant public health concern, especially for newborns and immunocompromised patients, causing a wide range of infections. Clinical outcomes associated with HCMV infection include congenital disease, graft rejection in transplant recipients, and life‐threatening ...
AlQahtani HY, Aleanizy FS, Alqahtani FY.
europepmc   +2 more sources

CAQ Corner: Basic concepts of transplant immunology

, 2022
Liver Transplantation, EarlyView.
Amanda Cheung, Josh Levitsky
wiley   +1 more source

Treatment of congenital cytomegalovirus infection [PDF]

Clinical and Experimental Pediatrics, 2023
Congenital cytomegalovirus (CMV) is the most common cause of congenital infection worldwide, the most common nongenetic cause of sensorineural hearing loss in children, and a cause of neurodevelopmental disorders in the brain.
Gyu Hong Shim
doaj   +1 more source

Valganciclovir Inhibits Human Adenovirus Replication and Pathology in Permissive Immunosuppressed Female and Male Syrian Hamsters

Viruses, 2015
Adenovirus infections of immunocompromised pediatric hematopoietic stem cell transplant patients can develop into serious and often deadly multi-organ disease. There are no drugs approved for adenovirus infections.
Karoly Toth, Baoling Ying, Ann E. Tollefson, Jacqueline F. Spencer, Lata Balakrishnan, John E. Sagartz, Robert Mark L. Buller, William S. M. Wold   +7 more
doaj   +1 more source

Valganciclovir as Add-On to Standard Therapy in Secondary Glioblastoma

Microorganisms, 2020
Patients with glioblastoma have a very poor prognosis despite aggressive therapeutic strategies. Cytomegalovirus has been detected in >90% of glioblastoma tumors.
Giuseppe Stragliotto, Mattia Russel Pantalone, Afsar Rahbar, Cecilia Söderberg-Nauclér   +3 more
doaj   +1 more source

Chronic Human Herpes Virus 8 Infection Successfully Treated With Valganciclovir

World Allergy Organization Journal, 2009
Background: A 57 year old Italian female with a 3 year history of constituitional symptoms with non-HIV Kaposi sarcoma was referred to the immunology clinic.
James J. Yun, MBBS, Veronica Preda, MBBS(Hons), BSc(Med), Brad Frankum, BMed(Hons), FRACP   +2 more
doaj   +1 more source

Treating HIV-associated cytomegalovirus retinitis with oral valganciclovir and intra-ocular ganciclovir by primary HIV clinicians in southern Myanmar: a retrospective analysis of routinely collected data

BMC Infectious Diseases, 2020
Background Cytomegalovirus retinitis (CMVR) is an opportunistic infection in HIV-infected people. Intraocular or intravenous ganciclovir was gold standard for treatment; however, oral valganciclovir replaced this in high-income countries. Low- and middle-
Jillian Murray, Adelene Hilbig, Theint Thida Soe, Win Le Shwe Sin Ei, Kyi Pyar Soe, Iza Ciglenecki   +5 more
doaj   +1 more source

Oral Administration of Valganciclovir Reduces Clinical Signs, Virus Shedding and Cell-Associated Viremia in Ponies Experimentally Infected with the Equid Herpesvirus-1 C₂₂₅₄ Variant

Pathogens, 2022
Equid alphaherpesvirus-1 (EHV-1) is one of the main pathogens in horses, responsible for respiratory diseases, ocular diseases, abortions, neonatal foal death and neurological complications such as equine herpesvirus myeloencephalopathy (EHM).
Côme J. Thieulent, Gabrielle Sutton, Marie-Pierre Toquet, Samuel Fremaux, Erika Hue, Christine Fortier, Alexis Pléau, Alain Deslis, Stéphane Abrioux, Edouard Guitton, Stéphane Pronost, Romain Paillot   +11 more
doaj   +1 more source

Optimising graft survival in endothelial keratoplasty for endothelial failure secondary to cytomegalovirus endotheliitis

Journal of Ophthalmic Inflammation and Infection, 2019
Background There is limited information regarding Descemet stripping automated endothelial keratoplasty (DSAEK) for endothelial failure secondary to cytomegalovirus (CMV) endotheliitis. Treatment is difficult with high recurrence rates.
Milton C. Chew, Donald T. Tan, Soon-Phaik Chee, Lim Li   +3 more
doaj   +1 more source

Hearing loss in children with congenital cytomegalovirus infection

Revista Portuguesa Otorrinolaringologia e Cirurgia de Cabeça e Pescoço, 2023
Objective: To study the prevalence of hearing loss in children with congenital Cytomegalovirus infection and the influence of the type of maternal infection, symptoms and neonatal treatment with valganciclovir.
Gonçalo Caetano Oliveira, Filipa Morgado, Mariana Santos, Clara Mota, Ricardo Matos, Raquel Robles, Rui Fonseca   +6 more
doaj   +1 more source