Equid alphaherpesvirus-1 (EHV-1) is one of the main pathogens in horses, responsible for respiratory diseases, ocular diseases, abortions, neonatal foal death and neurological complications such as equine herpesvirus myeloencephalopathy (EHM).
Côme J. Thieulent +11 more
doaj +1 more source
Ganciclovir penetrates into the cerebrospinal fluid of an infant with congenital cytomegalovirus infection [PDF]
Currently, there is no evidence whether ganciclovir, or its oral prodrug valganciclovir, penetrates into the cerebrospinal fluid of human infants treated for congenital cytomegalovirus infection.
Bizzarri, Bianca +6 more
core +2 more sources
Human Cytomegalovirus Infection in Haematopoietic Stem Cell Transplant Recipients and CAR-T Cell Recipients-PART 2: Antiviral Therapy and Virus-Specific T Cell Therapy for HCMV in Allo-HSCT. [PDF]
ABSTRACT Human cytomegalovirus (HCMV) reactivation is a common and significant complication after allogeneic haematopoietic stem cell transplantation (allo‐HSCT), causing potentially life‐threatening disease. Antiviral therapy approaches for HCMV are often limited by toxicities and the risk of developing antiviral drug resistance.
Sutrave G +7 more
europepmc +2 more sources
Hearing loss in children with congenital cytomegalovirus infection
Objective: To study the prevalence of hearing loss in children with congenital Cytomegalovirus infection and the influence of the type of maternal infection, symptoms and neonatal treatment with valganciclovir.
Gonçalo Caetano Oliveira +6 more
doaj +1 more source
Ganciclovir/valganciclovir prophylaxis decreases cytomegalovirus-related events and bronchiolitis obliterans syndrome after lung transplantation [PDF]
BACKGROUND: Until recently, cytomegalovirus (CMV) infection represented a major threat to lung transplant recipients. Preliminary studies have shown that antiviral prophylaxis might improve the outcome for these patients. METHODS: We extended our initial
Boehler, A +6 more
core +1 more source
Congenital cytomegalovirus infection is the most common congenital infection, occurs in 0.6-5% of newborns worldwide, and is considered the leading non-genetic cause of sensorineural hearing loss in children.
E. V. Antsiferova +6 more
doaj +1 more source
Acute reduction of microglia does not alter axonal injury in a mouse model of repetitive concussive traumatic brain injury [PDF]
The pathological processes that lead to long-term consequences of multiple concussions are unclear. Primary mechanical damage to axons during concussion is likely to contribute to dysfunction.
Bennett, Rachel E, Brody, David L
core +2 more sources
Congenital Cytomegalovirus Infection: A Narrative Review of the Issues in Screening and Management From a Panel of European Experts. [PDF]
Maternal primary and non-primary cytomegalovirus (CMV) infection during pregnancy can result in in utero transmission to the developing fetus. Congenital CMV (cCMV) can result in significant morbidity, mortality or long-term sequelae, including ...
Blázquez-Gamero, D +6 more
core +1 more source
Background There is limited information regarding Descemet stripping automated endothelial keratoplasty (DSAEK) for endothelial failure secondary to cytomegalovirus (CMV) endotheliitis. Treatment is difficult with high recurrence rates.
Milton C. Chew +3 more
doaj +1 more source
CMV Immunoglobulins for the Treatment of CMV Infections in Thoracic Transplant Recipients [PDF]
Intravenous ganciclovir and, increasingly, oral valganciclovir are now considered the mainstay of treatment for cytomegalovirus (CMV) infection or CMV disease.
Allison +34 more
core +3 more sources

