Results 21 to 30 of about 13,874 (194)

Oral Administration of Valganciclovir Reduces Clinical Signs, Virus Shedding and Cell-Associated Viremia in Ponies Experimentally Infected with the Equid Herpesvirus-1 C2254 Variant

open access: yesPathogens, 2022
Equid alphaherpesvirus-1 (EHV-1) is one of the main pathogens in horses, responsible for respiratory diseases, ocular diseases, abortions, neonatal foal death and neurological complications such as equine herpesvirus myeloencephalopathy (EHM).
Côme J. Thieulent   +11 more
doaj   +1 more source

Ganciclovir penetrates into the cerebrospinal fluid of an infant with congenital cytomegalovirus infection [PDF]

open access: yes, 2015
Currently, there is no evidence whether ganciclovir, or its oral prodrug valganciclovir, penetrates into the cerebrospinal fluid of human infants treated for congenital cytomegalovirus infection.
Bizzarri, Bianca   +6 more
core   +2 more sources

Human Cytomegalovirus Infection in Haematopoietic Stem Cell Transplant Recipients and CAR-T Cell Recipients-PART 2: Antiviral Therapy and Virus-Specific T Cell Therapy for HCMV in Allo-HSCT. [PDF]

open access: yesRev Med Virol
ABSTRACT Human cytomegalovirus (HCMV) reactivation is a common and significant complication after allogeneic haematopoietic stem cell transplantation (allo‐HSCT), causing potentially life‐threatening disease. Antiviral therapy approaches for HCMV are often limited by toxicities and the risk of developing antiviral drug resistance.
Sutrave G   +7 more
europepmc   +2 more sources

Hearing loss in children with congenital cytomegalovirus infection

open access: yesRevista Portuguesa Otorrinolaringologia e Cirurgia de Cabeça e Pescoço, 2023
Objective: To study the prevalence of hearing loss in children with congenital Cytomegalovirus infection and the influence of the type of maternal infection, symptoms and neonatal treatment with valganciclovir.
Gonçalo Caetano Oliveira   +6 more
doaj   +1 more source

Ganciclovir/valganciclovir prophylaxis decreases cytomegalovirus-related events and bronchiolitis obliterans syndrome after lung transplantation [PDF]

open access: yes, 2008
BACKGROUND: Until recently, cytomegalovirus (CMV) infection represented a major threat to lung transplant recipients. Preliminary studies have shown that antiviral prophylaxis might improve the outcome for these patients. METHODS: We extended our initial
Boehler, A   +6 more
core   +1 more source

Congenital cytomegalovirus infection: features of the clinical course and catamnesis according to own observations

open access: yesЖурнал инфектологии, 2022
Congenital cytomegalovirus infection is the most common congenital infection, occurs in 0.6-5% of newborns worldwide, and is considered the leading non-genetic cause of sensorineural hearing loss in children.
E. V. Antsiferova   +6 more
doaj   +1 more source

Acute reduction of microglia does not alter axonal injury in a mouse model of repetitive concussive traumatic brain injury [PDF]

open access: yes, 2014
The pathological processes that lead to long-term consequences of multiple concussions are unclear. Primary mechanical damage to axons during concussion is likely to contribute to dysfunction.
Bennett, Rachel E, Brody, David L
core   +2 more sources

Congenital Cytomegalovirus Infection: A Narrative Review of the Issues in Screening and Management From a Panel of European Experts. [PDF]

open access: yes, 2020
Maternal primary and non-primary cytomegalovirus (CMV) infection during pregnancy can result in in utero transmission to the developing fetus. Congenital CMV (cCMV) can result in significant morbidity, mortality or long-term sequelae, including ...
Blázquez-Gamero, D   +6 more
core   +1 more source

Optimising graft survival in endothelial keratoplasty for endothelial failure secondary to cytomegalovirus endotheliitis

open access: yesJournal of Ophthalmic Inflammation and Infection, 2019
Background There is limited information regarding Descemet stripping automated endothelial keratoplasty (DSAEK) for endothelial failure secondary to cytomegalovirus (CMV) endotheliitis. Treatment is difficult with high recurrence rates.
Milton C. Chew   +3 more
doaj   +1 more source

CMV Immunoglobulins for the Treatment of CMV Infections in Thoracic Transplant Recipients [PDF]

open access: yes, 2016
Intravenous ganciclovir and, increasingly, oral valganciclovir are now considered the mainstay of treatment for cytomegalovirus (CMV) infection or CMV disease.
Allison   +34 more
core   +3 more sources

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