Results 61 to 70 of about 13,874 (194)

Isolated Kidney Transplant in Primary Hyperoxaluria‐1 Enabled by Small Interfering RNA (siRNA) Therapy. Is It Time for Change? Case Report and Review of the Literature

Pediatric Transplantation, Volume 30, Issue 5, May 2026.
ABSTRACT Background Primary hyperoxaluria type 1 (PH1) is a rare genetic disorder characterized by excessive oxalate production that leads to nephrocalcinosis or nephrolithiasis and progressive kidney failure, associated with systemic oxalosis that is not reversed by dialysis. Pharmacological treatment is limited.
Shameer M. Habeeb, Eva Simkova, Samhar Al‐Akash, Hazem S. Awad, Haneen Yamin, Loai A. Eid, Watfa S. Aldhaheri, Waldo Concepcion, Martin Bitzan   +8 more
wiley   +1 more source

Adverse event profile differences between maribavir and valganciclovir: findings from the FDA adverse event reporting system

Frontiers in Pharmacology
BackgroundMaribavir and valganciclovir are pharmacotherapeutic options utilized in the management of cytomegalovirus (CMV) infection post-transplantation.
Haolin Teng, Shengnan Zhang, Jinyu Yu, Faping Li   +3 more
doaj   +1 more source

Disposition of valganciclovir during continuous renal replacement therapy in two lung transplant recipients [PDF]

, 2017
Objectives To determine whether valganciclovir 450 mg every 48 h for cytomegalovirus (CMV) prophylaxis provides appropriate ganciclovir exposure in solid organ transplant recipients during continuous renal replacement therapy (CRRT). Patients and methods
Aubert, J. D., Berger, M. M., Buclin, T., Decosterd, L. A., Meylan, P., Pascual, M., Perrottet, N., Robatel, C., Venetz, J. P.   +8 more
core  

Risk of Acute Kidney Injury Associated With Nephrotoxic Burden in Hospitalized Patients: A Scoping Review

Clinical Pharmacology &Therapeutics, Volume 119, Issue 4, Page 891-904, April 2026.
Limited evidence exists synthesizing the risk of acute kidney injury (AKI) associated with the concomitant administration of multiple nephrotoxic drugs, and even less examining the concept of nephrotoxic burden. The objective of this scoping review was to (1) identify definitions of nephrotoxic burden; (2) methods used to quantify (use of calculations)
Wafa Alatawi, Jessica L. Wallace, Dhakrit Rungkitwattanakul, Britney A. Stottlemyer, Tiffany L. Tran, Melanie Manis Reida, Sandra L. Kane‐Gill   +6 more
wiley   +1 more source

Incidencia y gravedad de la enfermedad por citomegalovirus en pacientes trasplantados renales que han recibido tratamiento anticipado o profilaxis con valganciclovir oral [PDF]

, 2012
Antecedentes: La infección por CMV es la más frecuente que sufren los receptores de trasplante de órgano sólido (TOS) en los primeros meses del trasplante.
Girado, Lluís, Pascual, Julio, Rodríguez Farré, Neus, Universitat Autònoma de Barcelona. Departament de Medicina, Universitat Autònoma de Barcelona. Facultat de Medicina   +4 more
core  

Newly Diagnosed AIDS with Multiple Opportunistic Infections Despite a Recent Negative Rapid HIV Test [PDF]

, 2013
Background Human Immunodeficiency Virus (HIV) is a fairly prevalent disease in the United States, with an estimated 1 million persons infected with HIV-1.1 Despite a decrease in Acquired Immunodeficiency Syndrome (AIDS), the prevalence of HIV is ...
Daniel, MD, PhD, Rene, Short, MD, MPH, William, Vakil, MD, Soham   +2 more
core   +2 more sources

Sensitive and Rapid Dual One‐Tube Recombinase Aided PCR Assays for the Simultaneous Detection of Cytomegalovirus, Epstein‐Barr Virus, Human Herpesvirus 6, and Herpes Simplex Virus 1/2 in Whole Blood From Children Undergoing Hematopoietic Stem Cell Transplantation

Journal of Medical Virology, Volume 98, Issue 4, April 2026.
ABSTRACT Early, rapid, and sensitive detection of cytomegalovirus (CMV), Epstein‐Barr virus (EBV), human herpesvirus 6 (HHV‐6), and herpes simplex virus Types 1/2 (HSV‐1/2) is critical for improving clinical outcomes in pediatric hematopoietic stem cell transplantation (HSCT).
Li Zhao, Mengchuan Zhao, Yuan Gao, Yanqing Tie, Yinghui Guo, Shuai Zhang, Yuxin Wang, Deran Ma, Zhili Shao, Zhishan Feng   +9 more
wiley   +1 more source

Efficacy of Low Dose Valganciclovir Prophylaxis for Cytomegalovirus Infection in Kidney Transplantation

Haseki Tıp Bülteni, 2020
Aim:Valganciclovir is the preferred drug for chemoprophylaxis for the prevention of cytomegalovirus (CMV) infection in kidney recipients. Low-dose (450 mg/day) valganciclovir use is gaining popularity because standard dose (900 mg/day) has negative ...
Ümit Özçelik, Nadir Alpay, Eryiğit Eren, Bora Uslu, Ahmet Cem Yardımcı   +4 more
doaj   +1 more source

Onset of valganciclovir resistance in two infants with congenital cytomegalovirus infection

International Journal of Infectious Diseases, 2020
Ganciclovir and its prodrug valganciclovir are elective treatments for cCMV. Neonates with important symptoms undergo 6 months of therapy to ameliorate/prevent symptoms and late sequelae, but evidence of resistance is emerging.
Francesca Garofoli, Giuseppina Lombardi, Micol Angelini, Giulia Campanini, Maurizio Zavattoni, Fausto Baldanti   +5 more
doaj   +1 more source

Anton’s syndrome [PDF]

, 2013
57-year-old male admitted to ITU with a severe Community Acquired Pneumonia. Stayed in ITU for about three weeks and during this period suffered an episode of deterioration which was attributed to multiple venous infarcts of the brain.
Portelli, Luke
core