Results 101 to 110 of about 9,445,211 (322)

Alternative scheme for frequency response function measurement of experimental-analytical dynamic substructuring

open access: yesJournal of Mechanical Engineering and Sciences, 2019
The accuracy of the predicted dynamic behaviour of an assembled structure using the frequency based substructuring (FBS) method is often found to be diverged from the experimental counterparts.
W. I. I. Wan Iskandar Mirza   +4 more
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Integrative network analysis suggests prioritised drugs for atopic dermatitis

open access: yesJournal of Translational Medicine
Background Atopic dermatitis (AD) is a prevalent chronic inflammatory skin disease whose pathophysiology involves the interplay between genetic and environmental factors, ultimately leading to dysfunction of the epidermis.
Antonio Federico   +8 more
doaj   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Microservices Validation: Methodology and Implementation [PDF]

open access: yes, 2015
Due to the wide spread of cloud computing, arises actual question about architecture, design and implementation of cloud applications. The microservice model describes the design and development of loosely coupled cloud applications when computing ...
Radchenko, G., Savchenko, D.
core  

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Effects of turbulent heat diffusion and viscosity on the simulation of turbulent mixing in autonomous PWR subchannel analysis software

open access: yesInternational Journal of Advanced Nuclear Reactor Design and Technology
In this paper the turbulent mixing models of several domestic autonomous PWR subchannel software under review by the national nuclear safety administration were evaluated and studied.
Bin Jia   +5 more
doaj   +1 more source

Uniform: The Form Validation Language [PDF]

open access: yes, 2016
Digital forms are becoming increasingly more prevalent but the ease of creation is not. Web Forms are difficult to produce and validate. This design project seeks to simplify this process.
Novak, Sawyer   +2 more
core   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Identification of damage based on frequency response function (FRF) data

open access: yesMATEC Web of Conferences, 2017
Mechanical joints, particularly fasteners such as bolted joints have a complex non-linear behaviour. The non-linearity might emerge from the material, geometry or by the contacts in the joints.
Sulaiman M. S. A.   +3 more
doaj   +1 more source

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