Results 61 to 70 of about 9,445,211 (322)

Efficient algorithms for decision tree cross-validation

, 2001
Cross-validation is a useful and generally applicable technique often employed in machine learning, including decision tree induction. An important disadvantage of straightforward implementation of the technique is its computational overhead.
Blockeel, Hendrik, Struyf, Jan
core   +4 more sources

Development and validation of computational models of cellular interaction [PDF]

, 2004
In this paper we take the view that computational models of biological systems should satisfy two conditions – they should be able to predict function at a systems biology level, and robust techniques of validation against biological models must be ...
Holcombe, W.M.L., Smallwood, R.H. [r.smallwood@shef.ac.uk], Walker, D.C.   +2 more
core   +1 more source

Parent Quality of Life at Two Years Following Their Child's Completion of Acute Lymphoblastic Leukemia Treatment

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Parents of children treated for acute lymphoblastic leukemia (ALL) often experience significant caregiver burden and disruption to their well‐being. While parent quality of life (QoL) during treatment is well characterized, little is known about outcomes during early survivorship.
Sara Dal Pra, Maria McCarthy, Michael Takagi, Cinzia De Luca   +3 more
wiley   +1 more source

MUUMI: an R package for statistical and network-based meta-analysis for multi-omics data integration

BMC Bioinformatics
Background Disentangling physiopathological mechanisms of biological systems through high-level integration of omics data has become a standard procedure in life sciences.
Simo Inkala, Michele Fratello, Giusy del Giudice, Giorgia Migliaccio, Angela Serra, Dario Greco, Antonio Federico   +6 more
doaj   +1 more source

CRISPR-mediated promoter editing of a cis-regulatory element of OsNAS2 increases Zn uptake/translocation and plant yield in rice

Frontiers in Genome Editing
Developing nutritious rice with a higher yield is one approach to alleviating the problem of micronutrient deficiency in developing countries, especially human malnutrition involving zinc and iron (Fe) deficiency, and achieving better adoption.
Yvonne Ludwig, Conrado Dueñas, Erwin Arcillas, Reena Jesusa Macalalad-Cabral, Ajay Kohli, Russell Reinke, Inez H. Slamet-Loedin   +6 more
doaj   +1 more source

Adjunctive Therapeutic Plasma Exchange in Refractory Adult‐Onset Still's Disease Complicated by Secondary Macrophage Activation Syndrome: A Single‐Center Experience

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Adult‐onset Still's disease (AOSD) complicated by macrophage activation syndrome (MAS) carries substantial mortality. The role of therapeutic plasma exchange (TPE) remains uncertain. Methods We retrospectively analyzed patients with AOSD‐MAS treated with TPE at a single‐center.
Masataka Ueda, Tomohiro Saito, Masahide Mizobuchi, Tomoki Shimomura, Saki Kawamori, Mitsuru Kawanishi, Natsuko Hattori, Jo Sugiyama, Satoshi Tsubata, Hanami Horiguchi, Kazuki Abe, Nao Iida, Yuki Kajio, Nao Oguro, Ryo Yanai, Hirokazu Honda   +15 more
wiley   +1 more source

The close interaction between hypoxia-related proteins and metastasis in pancarcinomas

Scientific Reports, 2022
Many primary-tumor subregions exhibit low levels of molecular oxygen and restricted access to nutrients due to poor vascularization in the tissue, phenomenon known as hypoxia.
Andrés López-Cortés, Lavanya Prathap, Esteban Ortiz-Prado, Nikolaos C. Kyriakidis, Ángela León Cáceres, Isaac Armendáriz-Castillo, Antonella Vera-Guapi, Verónica Yumiceba, Katherine Simbaña-Rivera, Gabriela Echeverría-Garcés, Jennyfer M. García-Cárdenas, Andy Pérez-Villa, Patricia Guevara-Ramírez, Andrea Abad-Sojos, Jhommara Bautista, Lourdes Puig San Andrés, Nelson Varela, Santiago Guerrero   +17 more
doaj   +1 more source

Effects of dark counts on digital silicon photomultipliers performance [PDF]

, 2013
Digital Silicon Photomultipliers (dSiPM) are novel light detector that integrates single-photon avalanche photodiodes and CMOS logic into a single silicon chip and have been used for developing new, high performance detectors for Positron Emission ...
Espana Palomares, Samuel, Marcinkowski, Radoslaw, Van Holen, Roel, Vandenberghe, Stefaan   +3 more
core  

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Validation of nonlinear PCA

, 2012
Linear principal component analysis (PCA) can be extended to a nonlinear PCA by using artificial neural networks. But the benefit of curved components requires a careful control of the model complexity.
A Herman, A Ilin, AN Gorban, B Chalmond, B Christiansen, B Efron, B Schölkopf, BW Lu, D DeMers, JB Tenenbaum, LK Saul, M Scholz, MA Kramer, Matthias Scholz, MR Hestenes, ND Lawrence, P Demartines, R Hecht-Nielsen, S Girard, S Harmeling, S Mika, ST Roweis, T Hastie, T Kohonen, WW Hsieh, WW Hsieh, WW Hsieh   +26 more
core   +1 more source