Results 71 to 80 of about 3,926,210 (300)
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Endothelial sensitivity to pro-fibrotic signals links systemic exposure to pulmonary fibrosis
Cell Death and DiseasePulmonary fibrosis (PF) is a life-threatening condition characterised by excessive extracellular matrix deposition and tissue scarring. While much of PF research has focused on alveolar epithelial cells and fibroblasts, endothelial cells have emerged as ...
Lena Möbus +7 more
doaj +1 more source
Ecological Validity of Performance Validity Testing [PDF]
Archives of Clinical Neuropsychology, 2014 Performance validity tests (PVTs) have been shown to relate to neuropsychological performance, but no studies have looked at the ecological validity of these measures. Data from 131 veterans with a history of mild traumatic brain injury from a multicenter Veterans Administration consortium were examined to determine the relation between scores on a ...
Sara M, Lippa +6 more
openaire +2 more sources
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
An Adaptive Dark-Target Algorithm for Retrieving Land AOD Applied to FY-4B/AGRI Data
IEEE Journal of Selected Topics in Applied Earth Observations and Remote SensingThe Fengyun 4B (FY-4B) as an operational satellite was launched on 3 June 2021. The advanced geostationary radiation imager (AGRI) aboard on the FY-4B has ability to monitor aerosols information.
Yidan Si +9 more
doaj +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
, 2016 This paper presents a theoretical account of legal validity. We begin with a very simple criterial account of validity and discuss the possibility of elimination of such concept by means of procedure described in Ross' paper Tû-Tû. Then we discuss more ambitious theoretical proposals concerning validity, advocated by Grabowski and ...
Michal Araszkiewicz, Pompeu Casanovas
openaire +4 more sources
, 2017 Genotypes of the 5 tag SNPs for the LY phenotype QLT peaks in the 18k validation ...
Thomas Lopdell (511314) +21 more
core +1 more source