Results 101 to 110 of about 3,609,753 (274)

Quality data validation: Comprehensive approach to environmental data validation [PDF]

, 1993
Environmental data validation consists of an assessment of three major areas: analytical method validation; field procedures and documentation review; evaluation of the level of achievement of data quality objectives based in part on PARCC parameters analysis and expected applications of data.
openaire   +2 more sources

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Two-Step Validation Approach for Tools To Study the DNA Repair Enzyme SNM1A. [PDF]

Chembiochem, 2023
Fay EM, Newton A, Berney M, El-Sagheer AH, Brown T, McGouran JF.   +5 more
europepmc   +1 more source

DESCRIPTIVE APPROACH TO CONTENT VALIDITY

EPH - International Journal of Medical and Health Science, 2015
This research addresses the lack of psychometrically some research instruments. Analysis of content validity was conducted by using descriptive method for some research measures. Descriptive analysis of median was conducted on the ratings from the expert panel members.
openaire   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Flow cytometry as an integrative method for the evaluation of vaccine immunogenicity: A validation approach. [PDF]

Biochem Biophys Rep, 2023
Gianchecchi E, Torelli A, Piu P, Bonifazi C, Ganfini L, Montomoli E.   +5 more
europepmc   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Same Classroom, Different Reality: Secondary School Students’ Perceptions of STEM Lessons—A Pioneering Study

Education Sciences
Our study is the first exploration of students’ situational perceptions of STEM lessons based on the DIAMONDS approach. This approach postulates eight perceptual dimensions: Duty, Intellect, Adversity, Mating, pOsitivity, Negativity, Deception, and ...
Lukas Ketscher, Heidrun Stoeger, Wilma Vialle, Albert Ziegler   +3 more
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Adaptation and validation study of the Indonesian version of the Global Psychotrauma Screen in an undergraduate student population

Comprehensive Psychiatry
Background: The high incidence of potentially traumatic events (PTEs) in Indonesia warrants early identification of those with probable trauma-related disorders in order to tailor prevention and intervention for trauma-related symptoms.
Indira Primasari, Chris M. Hoeboer, Anne Bakker, Miranda Olff   +3 more
doaj   +1 more source