Journal of Applied Pharmaceutical ResearchBackground: This study intended to introduce a robust ultra-performance liquid chromatography (UPLC) method for quantifying Mirvetuximab soravtansine-gynx (MSG) in pharmaceutical dosage forms. A systematic approach incorporating the Design of Experiments
K. V. Umamaheswara Rao, Neetu Shorgar
doaj +1 more source
Critical Response to Article "Integrated Network Pharmacology and Experimental Validation Approach to Investigate the Mechanisms of Stigmasterol in the Treatment of Rheumatoid Arthritis" [Letter]. [PDF]
Drug Des Devel Ther, 2023 Rinendyaputri R, Panjaitan NSD.
europepmc +1 more source
Molecular Oncology, EarlyView.A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath +13 more
wiley +1 more source
A Formal Validation Approach for XACML 3.0 Access Control Policy. [PDF]
Sensors (Basel), 2022 Caserio C, Lonetti F, Marchetti E.
europepmc +1 more source
Molecular Oncology, EarlyView.In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern +7 more
wiley +1 more source
Multi-Analyte Method for Antibiotic Residue Determination in Honey Under EU Regulation 2021/808
AntibioticsBackground/Objectives: Antibiotic detection in honey is challenging due to the complexity of this product, the typically low levels of residues, and the absence of Maximum Residue Levels (MRLs) for beehive products.
Helena Rodrigues +3 more
doaj +1 more source
Prediction and experimental validation approach to improve performance of novel hybrid bio-inspired 3D printed lattice structures using artificial neural networks. [PDF]
Sci Rep, 2023 Doodi R, Gunji BM.
europepmc +1 more source
Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids
Molecular Oncology, EarlyView.This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici +8 more
wiley +1 more source
A model for early failure prediction of blood pressure measurement devices in a stepped validation approach. [PDF]
J Clin Hypertens (Greenwich), 2022 Vischer AS +3 more
europepmc +1 more source
Cross-Validation Approaches for Replicability in Psychology [PDF]
Frontiers in Psychology, 2018 Atesh Koul +4 more
openaire +3 more sources