Results 121 to 130 of about 48,587,327 (320)
Cancer biomarker development from basic science to clinical practice [PDF]
, 2018 The amount of published literature on biomarkers has exponentially increased over the last two decades. Cancer biomarkers are molecules that are either part of tumour cells or secreted by tumour cells.
Ali, Asif +3 more
core
Osteoporotic and Neoplastic Compression Fracture Classification on Longitudinal CT
, 2016 Classification of vertebral compression fractures (VCF) having osteoporotic or neoplastic origin is fundamental to the planning of treatment. We developed a fracture classification system by acquiring quantitative morphologic and bone density ...
Burns, Joseph E. +3 more
core +1 more source
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
FEBS Letters, EarlyView.We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Status of the physics validation studies using Geant4 in ATLAS
, 2003 The new simulation for the ATLAS detector at LHC is performed using Geant4 in a complete OO/C++ environment. In this framework the simulation of the various test beams for the different ATLAS subdetectors offers an excellent opportunity to perform ...
Dell'Acqua, Andrea
core
FEBS Letters, EarlyView.Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source
Estudos de Psicologia (Campinas)The development and implementation of instruments with high psychometric standards for the assessment and monitoring of socio-emotional skills is considered an important step in the agenda for their promotion in educational contexts.
María Eugenia PANIZZA +2 more
doaj +1 more source
Mass spectrometry protein expression profiles in colorectal cancer tissue associated with clinico-pathological features of disease. [PDF]
, 2010 Background: Studies of several tumour types have shown that expression profiling of cellular protein extracted from surgical tissue specimens by direct mass spectrometry analysis can accurately discriminate tumour from normal tissue and in some cases can
Arulampalam, T +4 more
core
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Frequency-response techniques for documentation and improvement of rotorcraft simulators [PDF]
Pilot-in-the-loop characterizations are most naturally formulated in terms of end-to-end frequency responses, so a frequency-response-based method is the natural approach to assessing simulator dynamic fidelity.
Tischler, Mark B.
core +1 more source