Results 131 to 140 of about 2,104,233 (265)

Portuguese version of the CDR plus NACC FTLD: Validation studies. [PDF]

Alzheimers Dement (Amst), 2022
Lima M, Tábuas-Pereira M, Durães J, Faustino P, Simões MR, Kukull W, Knopman DS, Santana I.   +7 more
europepmc   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source

Adaptação transcultural Portugal-Brasil do Inventário de Burnout de Maslach para estudantes

Revista de Saúde Pública
OBJETIVO: Realizar a adaptação transcultural da versão em português do Inventário de Burnout de Maslach para estudantes e investigar sua confiabilidade, validade e invariância transcultural.
Juliana Alvares Duarte Bonini Campos, João Maroco   +1 more
doaj  

Comprehensive quantum chemical analysis, vibrational spectroscopy, molecular docking, ADMET, and in vitro validation studies of hydroxychloroquine-MRGPRX2 complex in IDH-wildtype glioblastoma. [PDF]

PLoS One
Demirag AD, Aksoy RA, Akman G, Kaya V, Yildirim M.   +4 more
europepmc   +1 more source

Systematic Review of Fitbit Charge 2 Validation Studies for Exercise Tracking. [PDF]

Transl J Am Coll Sports Med, 2022
Irwin C, Gary R.
europepmc   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

Evidence Supporting Utility of the Oral Cholate Challenge Test of Liver Function and Physiology to Aid Clinical Management: A Review of Analytical and Clinical Validation Studies. [PDF]

Gastro Hep Adv
Keaveny AP, Qureshi K, Shiffman M, Morgan TR, Reddy KR, Imperial JC, McRae MP, Shokati T, Everson GT.   +8 more
europepmc   +1 more source

Confirmatory and validation studies on experimental self-efficacy scale with applications to multiple scientific disciplines. [PDF]

Front Psychol, 2023
Kolil VK, Parvathy SU, Achuthan K.
europepmc   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

NRAS and SREBF1 identified as mitophagy-associated risk genes for rheumatoid arthritis through interpretable machine learning and experimental validation studies. [PDF]

BMC Rheumatol
Li H, Liu P, Han X, Si S, Li Z, Zhao C, Zhao X, Zhou X, Liu M.   +8 more
europepmc   +1 more source