Results 141 to 150 of about 52,085,429 (356)
Molecular Oncology, EarlyView.Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
Revista Brasileira de Geriatria e GerontologiaO artigo descreve a adaptação transcultural do Selection, Optimization and Compensation questionnaire (SOC) para o idioma português, para aplicação a idosos.
Sionara Tamanini de Almeida +2 more
doaj +1 more source
Validity and Reliability of the Persian Version of the Regret Scale in Iranian Elderly [PDF]
مجله علوم پزشکی صدراIntroduction: As people age, they often look back on their history to determine their accomplishments and shortcomings, which might cause them to feel regret. The present study was designed to assess the reliability and validity of the Persian version of
Arefe Eskandari +3 more
doaj +1 more source
Characteristics of studies included for validation.
, 2019 Characteristics of studies included for validation.
Saskia N. de Wildt (6836657) +3 more
core +1 more source
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Studies included in the validation analyses.
, 2014 The table contains the name of the study, a brief description of the patient population, the reported mean or median duration of the study, the treatment groups included in the validation, the number of participants at baseline and the number of ...
Michael Willis (643723) +4 more
core +1 more source
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
British medical journalAn external validation study evaluates the performance of a prediction model in new data, but many of these studies are too small to provide reliable answers.
R. Riley +7 more
semanticscholar +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source