Current status and progress of validation studies on the ICOPE scale: a scoping review. [PDF]
Zhao Y +8 more
europepmc +1 more source
Validation studies of verbal autopsy methods: a systematic review. [PDF]
Mahesh BPK +6 more
europepmc +1 more source
Structure‐forward targeting of claudins with synthetic binders
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Diagnostic Accuracy of Cardiovascular Disease Prediction Models: A Systematic Review and Meta-Analysis of Validation Studies. [PDF]
Rasouli MA +6 more
europepmc +1 more source
Correction: Validation studies of verbal autopsy methods: a systematic review. [PDF]
Mahesh BPK +6 more
europepmc +1 more source
Discerning protein pools by selective staining with self‐labeling tags
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley +1 more source
Bayesian Sample Size Calculations for External Validation Studies of Risk Prediction Models. [PDF]
Sadatsafavi M +4 more
europepmc +1 more source
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
Objetivos. Evaluar las propiedades psicométricas y desarrollar una versión reducida de la nueva escala de ansiedad. Materiales y métodos. La nueva escala de ansiedad de 130 ítems (NEA-130) se aplicó a 254 pacientes psiquiátricos ambulatorios de un ...
Antonio Lozano-Vargas +1 more
doaj
Laser doppler holography for choroidal blood flow assessment: a systematic review of technical capabilities, validation studies, and clinical applications. [PDF]
Marco Giammanco M +2 more
europepmc +1 more source

