Results 151 to 160 of about 48,587,327 (320)

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source

Validation of questionnaire used in epidemiological blood pressure studies

Open Medicine, 2012
Stawińska-Witoszyńska Barbara, Kowalska Małgorzata, Krzyżaniak Alicja, Krzywińska-Wiewiorowska Małgorzata, Krzych Łukasz   +4 more
doaj   +1 more source

Dependence module of the MINI plus adapted for sugar dependence: psychometric properties Módulo de dependência do MINI plus adaptado para dependência de açúcar: propriedades psicométricas

Psicologia: Reflexão e Crítica, 2013
This study aimed to analyze the factorial structure and the scale of measurement of the items for dependence of the Diagnostic and Statistical Manual of Mental Disorders (DSM-IV) adapted for sugar consumption in order to verify if the structural ...
Marco Aurélio Camargo da Rosa, Cristiano Mauro Assis Gomes, Neusa Sica da Rocha, Felix Henrique Paim Kessler, Sonia Maria Blauth de Slavutzky, Efigênia Ferreira e Ferreira, Flavio Pechansky   +6 more
doaj  

The association between differentiation of self and romantic relationship outcomes and the mediating role of communication behaviors [PDF]

Master of ScienceSchool of Family Studies and Human ServicesJared R. AndersonThis study examined the association between level of differentiation of self on romantic relationship outcomes (i.e., attachment, relationship satisfaction, and gridlock) while,
Wilson, Christina Emma
core  

In vitro properties of patient serum predict clinical outcome after high dose rate brachytherapy of hepatocellular carcinoma

Molecular Oncology, EarlyView.
Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser, Jan Niklas Schäfer, Shraga Nahum Goldberg, Philipp Maximilian Kazmierczak, Moritz Nikolaus Gröper, Philipp Franz Linden, Elif Öcal, Tanja Burkard, Stefanie Corradini, Najib Ben Khaled, Moritz Wildgruber, Max Seidensticker, Jens Ricke, Matthias Stechele, Marianna Alunni‐Fabbroni   +14 more
wiley   +1 more source

Correction: Validation studies of verbal autopsy methods: a systematic review. [PDF]

BMC Public Health, 2023
Mahesh BPK, Hart JD, Acharya A, Chowdhury HR, Joshi R, Adair T, Hazard RH.   +6 more
europepmc   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

Portuguese version of the CDR plus NACC FTLD: Validation studies. [PDF]

Alzheimers Dement (Amst), 2022
Lima M, Tábuas-Pereira M, Durães J, Faustino P, Simões MR, Kukull W, Knopman DS, Santana I.   +7 more
europepmc   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Confirmatory and validation studies on experimental self-efficacy scale with applications to multiple scientific disciplines. [PDF]

Front Psychol, 2023
Kolil VK, Parvathy SU, Achuthan K.
europepmc   +1 more source