Results 81 to 90 of about 4,269,345 (275)

Semantic and cultural equivalence of the Intergenerational Exchanges Attitude Scale (IEAS)

Revista Brasileira de Geriatria e Gerontologia
Introduction: Understanding the multidimensionality of attitudes originating from exchanges between different generations is fundamental for the establishment of intergenerational cooperation and the reduction of stereotypes and prejudices.
Roberta dos Santos Tarallo, Anita Liberalesso Neri, Meire Cachioni   +2 more
doaj   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Validation of the method for determination of related impurities in the active antiviral ingredient of enisamium iodide

Zaporožskij Medicinskij Žurnal, 2018
The aim of the work. To validate a method for the related impurities determination in the enisamium iodide active pharmaceutical ingredient (API) by means of high-performance liquid chromatography (HPLC).
O. V. Burmaka, S. M. Hureieva, V. M. Marhitych   +2 more
doaj   +1 more source

Validation of back-calculation equations for juvenile bluefish (Pomatomus saltatrix) with the use of tetracycline-marked otoliths [PDF]

, 2007
In recent years, a decrease in the abundance of bluefish (Pomatomus saltatrix) has been observed (Fahay et al., 1999; Munch and Conover, 2000) that has led to increased interest in a better understanding the life history of the species.
Oliveira, Kenneth, Roemer, Marja E.
core  

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Validación de la escala ESTE para medir la soledad de la población adulta Validação da escala ESTE para medir a solidão da população adulta ESTE scale validation to measure loneliness in adult population

Investigación y Educación en Enfermería, 2010
Objetivo. Validar la escala de medición de la soledad ESTE en población adulta que asiste a los grupos de la tercera edad del municipio de Bello (Colombia). Metodología. Estudio descriptivo de corte transversal.
Jairo León Cardona Jiménez, María Mercedes Villamil Gallego, Eucaris Henao Villa, Ángela Quintero Echeverri   +3 more
doaj  

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Validity of Canadian studies [PDF]

BMJ, 2004
EDITOR—My detailed response to the news report by White on the validity of my studies is available on bmj.com.1 2 The report contains several inaccuracies. The typographic error of writing SE instead of SD had already been acknowledged. We did not ask the subjects to remember and recount 50 digits.
openaire   +2 more sources