Results 91 to 100 of about 2,879,474 (307)

CX3CL1 in Early Detection of Alzheimer's Disease: Plasma Dynamics Across Age and Disease Stages

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Backgrounds Alzheimer's disease (AD) is characterized by amyloid‐beta plaques, tau tangles, and neuroinflammation. C‐X3‐C motif chemokine ligand 1 (CX3CL1, also known as fractalkine), a neuroimmune chemokine implicated in AD pathogenesis, shows inconsistent alterations in plasma/serum across studies.
Ling Wang, Yujie Liu, Fei Li, Xuelin Li, Lanlan Li, Jie Zhang, Yali Xu   +6 more
wiley   +1 more source

Psychometric Assessment of the Persian Version of the Structured Multidisciplinary Work Evaluation Tool (SMET) Questionnaire among Nurses [PDF]

بهداشت و ایمنی کار
Introduction: Nurses play a crucial role in hospital settings, often undertaking demanding tasks that exceed their physical and cognitive capacities.
MasoumehAlsadat Mousavi kani, Zeinab Kazemi, Marzieh Izadi Laybidi, Ehsan Garosi, Jamileh Abolghasemi, Mohammad Sadegh Ghasemi   +5 more
doaj  

Value of MRI Outcomes for Preventive and Early‐Stage Trials in Spinocerebellar Ataxias 1 and 3

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To examine the value of MRI outcomes as endpoints for preventive and early‐stage trials of two polyglutamine spinocerebellar ataxias (SCAs). Methods A cohort of 100 participants (23 SCA1, 63 SCA3, median Scale for the Assessment and Rating of Ataxia (SARA) score = 5, 42% preataxic, and 14 gene‐negative controls) was scanned at 3T up ...
Thiago J. R. Rezende, Emilien Petit, Young Woo Park, Sophie Tezenas du Montcel, James M. Joers, Jonathan M. DuBois, H. Moore Arnold, Michal Povazan, Ipek Özdemir, Guita Banan, Romain Valabregue, Philipp Ehses, Jennifer Faber, Chiadi U. Onyike, Peter B. Barker, Jeremy D. Schmahmann, Eva‐Maria Ratai, Sub H. Subramony, Thomas H. Mareci, Khalaf O. Bushara, Henry Paulson, Thomas Klockgether, Alexandra Durr, Tetsuo Ashizawa, Christophe Lenglet, Gülin Öz, READISCA Investigators   +26 more
wiley   +1 more source

Adolescent participation characteristics: Development and initial psychometric properties of the adolescents participation questionnaire

Scandinavian Journal of Occupational Therapy
Background Adolescents’ participation in daily activities is linked to positive effects, including improved academic performance, reduced school dropout and delinquency rates, increased social engagement, and influences well-being.
Yael Lavie-Pitaro, Naomi Weintraub, Anat Golos   +2 more
doaj   +1 more source

Fluid Biomarkers of Disease Burden and Cognitive Dysfunction in Progressive Supranuclear Palsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Identifying objective biomarkers for progressive supranuclear palsy (PSP) is crucial to improving diagnosis and establishing clinical trial and treatment endpoints. This study evaluated fluid biomarkers in PSP versus controls and their associations with regional 18F‐PI‐2620 tau‐PET, clinical, and cognitive outcomes.
Roxane Dilcher, Charles B. Malpas, Stuart J. McDonald, William T. O’Brien, Craig Despott, Kelly L. Bertram, Matthew P. Pase, Lukas Frontzkowski, Meng Law, Terence J. O’Brien, Lucy Vivash   +10 more
wiley   +1 more source

Cross-cultural adaptation, reliability, and validity of a Chinese version of the swallowing impairment score

Frontiers in Psychology
IntroductionThe impact of thyroidectomy on swallowing is prevalent. Difficulties in swallowing can lead to malnutrition, destress and a decline in quality of life.
Weiwei Xu, Yuqiu Zhou, Yuxia Fan, Man Jiang, Guihua Li, Hui Guo, Qing Yang, Dingfen Zeng   +7 more
doaj   +1 more source

Complementarity of Long‐Reads and Optical Mapping in Parkinson's Disease for Structural Variants

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Long‐read sequencing and optical genome mapping technologies have the ability to detect large and complex structural variants. This has led to the discovery of novel pathogenic variants in neurodegenerative movement disorders. Thus, we aimed to systematically compare the SV detection capabilities of OGM and ONT in Parkinson's disease.
André Fienemann, Theresa Lüth, Susen Schaake, Carolin Gabbert, Marius Möller, Hauke Busch, Katja Lohmann, Jonas A. Gustafson, Danny E. Miller, Kensuke Daida, Manabu Funayama, Nobutaka Hattori, Samia Ben Sassi, Faycel Hentati, Matthew J. Farrer, Kristian K. Ullrich, Christine Klein, Joanne Trinh   +17 more
wiley   +1 more source

Validity and reliability of the Chinese version of the Break-up Distress Scale for college students

Frontiers in Psychology
ObjectiveThis study aimed to revise the validity and reliability of the Chinese version of the Break-up Distress Scale (BDS) for college students.MethodsA total of 669 college students with breakup experience in the last 6 months were selected using the ...
Xin Qiao, Tingting Zhan, Tingting Zhan, Yaoguo Geng   +3 more
doaj   +1 more source

Validity of a Wearable Digital Insole for Assessing Gait ON and OFF in Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Gait impairment is a distinctive symptom of Parkinson's disease that negatively impact mobility. We assessed the validity of wearable digital insoles against a validated reference gait analysis system for measuring select gait characteristics in patients with Parkinson's disease. Methods A comparative analysis between digital insoles
Deborah A. Hall, Kimberly Kwei, Rolando J. Acosta, Bharatkumar Koyani, Erin Robertson, Pratyush Rai, Roland Barge, Emily Timm, Nicollette L. Purcell, Natasha Desai, Dhanesh Patel, Ana‐Maria Visoiu‐Knapp, Samuel Stuart, Rinol Alaj, Matthew F. Wipperman, Oren Levy, Joan A. O'Keefe   +16 more
wiley   +1 more source

Adaptation and Psychometric Evaluation of the Evidence-Based Practice Mentoring Scale into Turkish

Ebelik ve Sağlık Bilimleri Dergisi
Objective: This study aimed to adapt the Evidence-Based Practice Mentorship Scale (EBP-Mentorship Scale) into Turkish and to evaluate its psychometric properties among Turkish nurses.Methods: This methodological study was conducted with 152 nurses ...
Elanur Uludağ, Fadime Ulupınar, Yasemin Erden   +2 more
doaj   +1 more source