Results 91 to 100 of about 4,179,049 (359)

Validity of the expected Euler characteristic heuristic [PDF]

open access: yes, 2005
We study the accuracy of the expected Euler characteristic approximation to the distribution of the maximum of a smooth, centered, unit variance Gaussian process f.
Adler, Robert J.   +2 more
core   +2 more sources

Tonic signaling of the B‐cell antigen‐specific receptor is a common functional hallmark in chronic lymphocytic leukemia cell phosphoproteomes at early disease stages

open access: yesMolecular Oncology, EarlyView.
B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez   +17 more
wiley   +1 more source

Becoming a Posthuman Systemic Nomad

open access: yesMurmurations, 2019
We live in a complex, globalised world. Everything is connected and still many of us feel detached, disconnected from other entities on earth. We might sleepwalk into a global ecological crisis and therefore we need to develop new ways of living together
Robert Van Hennik
doaj   +1 more source

Modal Ω-Logic: Automata, Neo-Logicism, and Set-Theoretic Realism [PDF]

open access: yes, 2019
This essay examines the philosophical significance of $\Omega$-logic in Zermelo-Fraenkel set theory with choice (ZFC). The duality between coalgebra and algebra permits Boolean-valued algebraic models of ZFC to be interpreted as coalgebras.
A Baltag   +45 more
core   +9 more sources

Validating “Data Validation” [PDF]

open access: yesComputer, 2021
Norita Ahmad, Kevin Dias
openaire   +2 more sources

Ubiquitination of transcription factors in cancer: unveiling therapeutic potential

open access: yesMolecular Oncology, EarlyView.
In cancer, dysregulated ubiquitination of transcription factors contributes to the uncontrolled growth and survival characteristics of tumors. Tumor suppressors are degraded by aberrant ubiquitination, or oncogenic transcription factors gain stability through ubiquitination, thereby promoting tumorigenesis.
Dongha Kim, Hye Jin Nam, Sung Hee Baek
wiley   +1 more source

Turkish version of the Tilburg Frailty Indicator

open access: yesClinical Interventions in Aging, 2019
Yildiray Topcu, Fatih Tufan, Cihan Kilic Department of Geriatrics, Istanbul School of Medicine, Istanbul University, Istanbul, Turkey Background: Recently frailty has drawn significant interest as an important predictor of several clinically relevant ...
Topcu Y, Tufan F, Kilic C
doaj  

On the Requirements of Legal Justice of the Administrative Law Enforcement Activity

open access: yesСибирское юридическое обозрение, 2020
The article considers issues of understanding by the administrative-legal science of legal justice of the law-enforcement activity of executive authorities, other public administration bodies.
S. V. Yarkovoy
doaj  

HDAC4 regulates apoptosis in Acan‐CreERT2;HDAC4d/d mice with osteoarthritis by downregulating ATF4

open access: yesFEBS Open Bio, EarlyView.
Using the AcanCreERT2;HDAC4fl/fl genetic mouse model, we further investigated the role of histone deacetylase 4 (HDAC4) in chondrocyte apoptosis. We found that knocking down HDAC4 may be associated with chondrocyte apoptosis by upregulating the activating transcription factor 4 (ATF4)/CAAT/enhancer binding protein homologous (CHOP) signaling pathway ...
Jingrui Huang   +11 more
wiley   +1 more source

Psychometric properties of a Farsi version of the Dutch Boredom Scale Questionnaire (DUBS) in Iranian University of Medical Sciences employees

open access: yesSalāmat-i kār-i Īrān, 2020
Background and Aim: Boredom is a psychological phenomenon which is caused by many factors and it can be accompanied by undesirable effects such as reduction of professional performance. Boredom in the workplace leads to a decrease in job satisfaction and
Shahnaz Rimaz   +7 more
doaj  

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