Results 61 to 70 of about 2,879,474 (307)

Tumor‐stromal crosstalk and macrophage enrichment are associated with chemotherapy response in bladder cancer

FEBS Open Bio, EarlyView.
Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold, Janik Riese, Lancelot Seillier, Mark Kühnel, Julia Pannhausen, Charlotte O. J. Fröhlich, Christian Martin, Peter Boor, Matthias Saar, Danny D. Jonigk, Nadine T. Gaisa, Michael Rose   +11 more
wiley   +1 more source

Exon 7 splicing of ERα predicts poor prognosis and increases phenotypic heterogeneity in luminal a subtype breast cancer

FEBS Open Bio, EarlyView.
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui, Taobo Hu, Thomson Christian Husein, Wai Hei Shek, Bingrong Chen, Depeng Wang, Shu Wang, Weichuan Yu, Xiaodan Fan, Mengping Long, Toyotaka Ishibashi   +10 more
wiley   +1 more source

Predicting and Comparing the Subjective Health Experience of Older Cancer Survivors and Non‐Cancer Survivors: A Modeling Approach

Aging and Cancer, EarlyView.
This study underscores the significant influence of frailty and vitality on the subjective health experience of older cancer survivors with acceptance and control emerging as salient mediators. These findings affirm the conceptual and empirical robustness of the model highlighting its potential utility in shaping future interventions for older cancer ...
Damien S. E. Broekharst, Sjaak Bloem, Eline J. Mertens, Nathascha Hanzen, Michel van Agthoven   +4 more
wiley   +1 more source

Acute stress and fear scales during the COVID-19 pandemic: development and evaluation in a Costa Rican sample

Población y Salud en Mesoamérica
Objective: In the context of the pandemic due to SARS-CoV-2, concerns were raised about how to adequately assess its impact on the wellbeing of the population.
Ana María Jurado-Solórzano, Gloriana Rodríguez-Arauz, Vanessa Smith-Castro, Mariano Rosabal-Coto, Sebastián Saborío, Henriette Raventós-Vorst, Benjamín Reyes-Fernández   +6 more
doaj   +1 more source

Validation of functional assessment of chronic illness therapy - spiritual well-being scale (FACIT-Sp-12) in Serbian oncology patients [PDF]

Psihologija
The Functional Assessment of Chronic Illness Therapy – Spiritual Well-Being scale (FACIT-Sp-12) is a 12-item questionnaire designed to assess spiritual well-being in individuals diagnosed with cancer and other chronic illnesses.
Klikovac Tamara, Rajić Isidora, Lazić Milica   +2 more
doaj   +1 more source

The Aging Blood: Cellular Origins, Circulating Drivers, and Therapeutic Potential

Aging and Cancer, EarlyView.
As a conduit linking all organs, the blood system both reflects and actively drives systemic aging. This review highlights how circulating pro‐aging and antiaging factors and age‐associated hematopoietic stem cell dysfunction contribute to immunosenescence and multi‐organ decline, positioning the hematopoietic system as a target for aging intervention.
Hanqing He, Jianwei Wang
wiley   +1 more source

Visual Recovery Reflects Cortical MeCP2 Sensitivity in Rett Syndrome

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Rett syndrome (RTT) is a devastating neurodevelopmental disorder with developmental regression affecting motor, sensory, and cognitive functions. Sensory disruptions contribute to the complex behavioral and cognitive difficulties and represent an important target for therapeutic interventions.
Alex Joseph Simon, Nathalie Picard, Valeria d'Andrea, Enchi Chang, Joseph Leffler, Eleonora Centofante, Matthew Taylor, Francesca Bardi, Francesca Cavicchiolo, Takao K. Hensch, Stefano Panzeri, Chinfei Chen, Michela Fagiolini   +12 more
wiley   +1 more source

Psychometric evaluation of the reliability and validity of the literacy of suicide scale among Chinese nurses

Frontiers in Psychology
ObjectiveThis study aimed to Sinicize the Literacy of Suicide Scale (LOSS) and to test the reliability and validity of the LOSS with Chinese nurses.MethodsAfter authorization was obtained from the original author, the LOSS was translated into Chinese and
Zheshu Xie, Juanjuan Lin, Ying Fan, Feirong Tan, Yumei Zhou, Xing Liu   +5 more
doaj   +1 more source

Who Validates the Validators?

, 2022
Given a fip:Metadata-schema and a validator for it, such as a sh:Validator or a JSON Schema, how do you determine that the validator is…valid? That it speaks the desired fip:Knowledge-representation-language, that it knows all the terms in a desired fip:Structured-vocabulary and checks their usage against a desired fip:Semantic-model?
openaire   +1 more source

Frailty Exacerbates Disability in Progressive Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background To evaluate frailty in severe progressive multiple sclerosis (PMS) and to investigate the underlying mechanisms. Methods This prospective, cross‐sectional, multicenter study enrolled a late severe PMS group requiring skilled nursing (n = 53) and an age, sex, and disease duration‐matched control PMS group (n = 53).
Taylor R. Wicks, Anna Wolska, Diala Ghazal, Dejan Jakimovski, Bianca Weinstock‐Guttman, Alexander Burnham, Niels Bergsland, Michael G. Dwyer, Alan T. Remaley, Robert Zivadinov, Murali Ramanathan   +10 more
wiley   +1 more source