Results 61 to 70 of about 4,331,982 (336)

Peripheral blood proteome biomarkers distinguish immunosuppressive features of cancer progression

Molecular Oncology, EarlyView.
Immune status significantly influences cancer progression. This study used plasma proteomics to analyze benign 67NR and malignant 4T1 breast tumor models at early and late tumor stages. Immune‐related proteins–osteopontin (Spp1), lactotransferrin (Ltf), calreticulin (Calr) and peroxiredoxin 2 (Prdx2)–were associated with systemic myeloid‐derived ...
Yeon Ji Park, Jae Won Oh, Hyewon Chung, Jung Won Kwon, Yi Rang Na, Kwang Pyo Kim, Seung Hyeok Seok   +6 more
wiley   +1 more source

The Validity of Aquinas’ Third Way [PDF]

, 1971
This article argues for the formal validity of and the truth of the premises and conclusion of a version of Aquinas' "Third Way" that says: If each of the parts of nature is contingent, the whole of nature is contingent.
Edwards, Rem B.
core   +1 more source

Highly multiplexed digital PCR assay for simultaneous quantification of variant allele frequencies and copy number alterations of KRAS and GNAS in pancreatic cancer precursors

Molecular Oncology, EarlyView.
Combining melting curve analysis enhances the multiplexing capability of digital PCR. Here, we developed a 14‐plex assay to simultaneously measure single nucleotide mutations and amplifications of KRAS and GNAS, which are common driver genes in pancreatic cancer precursors. This assay accurately quantified variant allele frequencies in clinical samples
Junko Tanaka, Tatsuo Nakagawa, Yusuke Ono, Yoshio Kamura, Takeshi Ishida, Hidemasa Kawabata, Kenji Takahashi, Hiroki Sato, Andrew S. Liss, Yusuke Mizukami, Takahide Yokoi   +10 more
wiley   +1 more source

Validity of adiabaticity in Cavity QED

, 2005
This paper deals with the concept of adiabaticity for fully quantum mechanically cavity QED models. The physically interesting cases of Gaussian and standing wave shapes of the cavity mode are considered.
A. D. Shapere, A. Messiah, H. Lefebvre-Brion, J. Larson, J. Larson, J. Larson, M. Born, R. R. Schlicher, S. Haroche, S. Stenholm   +9 more
core   +1 more source

Psychometric properties of the Chinese (Putonghua) version of the Oxford Cognitive Screen (OCS-P) in subacute poststroke patients without neglect [PDF]

, 2018
Background Oxford Cognitive Screen is designed for assessing cognitive functions of poststroke patients.This study was aimed to assess the psychometric properties of the Chinese (Putonghua) version of theOxford Cognitive Screen-Putonghua (OCS-P) for use ...
Chan, Chetwyn C. H., Chen, Li-dian, Chien, Chi-wen, Demeyere, Nele, Hong, Wen-jun, Lau, Stephen C. L., Lee, Tatia M. C., Leung, Man-tak, Tao, Jing, Wong, Alex W. K., Yang, Shan-li   +10 more
core   +4 more sources

ShcD adaptor protein drives invasion of triple negative breast cancer cells by aberrant activation of EGFR signaling

Molecular Oncology, EarlyView.
We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau, Hayley S. Smith, Begüm Alural, Claire E. Martin, Laura A. New, Manali Tilak, Sara L. Banerjee, Hannah N. Robeson, Nicolas Bisson, Anne‐Claude Gingras, Jasmin Lalonde, Nina Jones   +11 more
wiley   +1 more source

Practical challenges in data‐driven interpolation: Dealing with noise, enforcing stability, and computing realizations

International Journal of Adaptive Control and Signal Processing, EarlyView., 2023
Summary In this contribution, we propose a detailed study of interpolation‐based data‐driven methods that are of relevance in the model reduction and also in the systems and control communities. The data are given by samples of the transfer function of the underlying (unknown) model, that is, we analyze frequency‐response data.
Quirin Aumann, Ion Victor Gosea
wiley   +1 more source

Supply chain integration scales validation and benchmark values

Journal of Industrial Engineering and Management, 2013
Purpose: The clarification of the constructs of the supply chain integration (clients, suppliers, external and internal), the creation of a measurement instrument based on a list of items taken from earlier papers, the validation of these scales and a ...
Juan A. Marin-Garcia, Rafaela Alfalla-Luque, Carmen Medina-López   +2 more
doaj   +1 more source

Consistency and validity of interdisciplinarity measures

, 2019
Measuring interdisciplinarity is a pertinent but challenging issue in quantitative studies of science. There seems to be a consensus in the literature that the concept of interdisciplinarity is multifaceted and ambiguous.
Schneider, Jesper Wiborg, Wang, Qi
core   +1 more source

Chemoresistome mapping in individual breast cancer patients unravels diversity in dynamic transcriptional adaptation

Molecular Oncology, EarlyView.
This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani, Gilgi Friedlander, Gili Perry, Nora Balint‐Lahat, Shlomit Gilad, Dana Morzaev‐Sulzbach, Anjana Shenoy, Noa Bossel Ben‐Moshe, Anya Pavlovsky, Rinat Bernstein‐Molho, Eytan Domany, Iris Barshack, Tamar Geiger, Bella Kaufman, Einav Nili Gal‐Yam   +14 more
wiley   +1 more source