Results 131 to 140 of about 34,671 (226)

The multifaceted roles of the ACSL family in cancer: Metabolic reprogramming, ferroptosis regulation and tumour immune microenvironment remodelling

Clinical and Translational Medicine, Volume 16, Issue 3, March 2026.
The acyl‐CoA synthetase long‐chain (ACSL) family consists of five members, which exhibit a synergistic effect in promoting tumour lipid metabolism for energy supply. Specifically, ACSL3 and ACSL4 have antagonistic effects on the mechanisms related to ferroptosis in tumour cells.
Haocai Li, Weijian Wang, Juncheng Zhan, Yuxiang Xiao, Xiaoping Chen, Chen Su, Peng Zhu   +6 more
wiley   +1 more source

Molecular Investigation of the Effects of Two Antiepileptic Drugs (Valproic Acid and Levetiracetam) on Alveolar Bone Under Orthodontic Force. [PDF]

Medicina (Kaunas)
Bayindir-Durna N, Uckan M, Aydin S, Ozdemir S.   +3 more
europepmc   +1 more source

Maternal High‐Fat Diet and Neonatal LPS Exposure Prolong USV Sequences and Shift Call‐Type Repertoires in Neonatal Rats

Developmental Psychobiology, Volume 68, Issue 2, March 2026.
ABSTRACT Rodent pups emit ultrasonic vocalizations (USVs) to solicit maternal care, enhancing survival. Inflammatory stressors, such as maternal high‐fat diet (mHFD) and neonatal lipopolysaccharide (nLPS) exposure, affect neonatal neurodevelopment and behavior.
Mansi Kamlesh Purohit, Ingrid Woo, Mouly Rahman, Sameera Abuaish, Patrick O. McGowan   +4 more
wiley   +1 more source

Therapeutic timing limitations of postnatal darbepoetin in a valproic acid rat model of Autism Spectrum Disorder. [PDF]

PLoS One
İpek ÖY, Kirboğa T, Babur E, Dursun N, Süer C.   +4 more
europepmc   +1 more source

Insect‐Derived Bioactives for Glycemic Control and Gut Health: A Review

Food Frontiers, Volume 7, Issue 2, March 2026.
Insect‐derived bioactive compounds (e.g., peptides, polysaccharides) effectively regulate blood glucose through dual mechanisms: directly inhibiting carbohydrate‐digesting enzymes and glucose transporters, and indirectly modulating gut microbiota to enhance intestinal barrier integrity.
Chaoyi Lv, Yuanyuan Huang, Mokhtar Dabbour, Benjamin Kumah Mintah, Ronghai He, Haile Ma   +5 more
wiley   +1 more source

Maternal Immune Stimulation With Interferon-Gamma Limits Embryonic Valproic Acid Induced Apoptotic Gene Expression. [PDF]

Birth Defects Res
Frascella D, Mallela MK, Cullen R, Hrubec TC.   +3 more
europepmc   +1 more source

Mechanisms of spinal glial activation in chemotherapy‐induced peripheral neuropathy: Focus on microglia and astrocytes

Ibrain, Volume 12, Issue 1, Page 65-85, Spring 2026.
Chemotherapy‐induced peripheral neuropathy (CIPN) remains a major clinical challenge, with central sensitization considered an important pathological mechanism in its occurrence and persistence. This review focuses on spinal astrocytes and microglia, systematically summarizing the pathological mechanisms of spinal glial cells involved in CIPN caused by
Long Gu, Song Cao, Yonghuai Feng
wiley   +1 more source

Hyperactivity is linked to elevated cortisol levels: comprehensive behavioral analysis in the prenatal valproic acid-induced marmoset model of autism. [PDF]

Transl Psychiatry
Nakamura M, Nakamura T, Nakagami A, Nakagaki K, Kawai N, Ichinohe N.   +5 more
europepmc   +1 more source

Potential neuroprotective and therapeutic agents and their mechanisms for irradiation‐induced brain injury

Ibrain, Volume 12, Issue 1, Page 96-122, Spring 2026.
In this review, agents such baicalein, troxerutin, epigallocatechin gallate, quercetin, melatonin, valproic acid, lithium, neurosteroid progesterone, as well as minocycline have been implicated as neuroprotective agents for irradiation‐induced neurological deficits. Also, agents such as glucocorticoids, methylphenidate, vitamin E, bisdemethoxycurcumin,
Seidu A. Richard, Vivian Kapio Abem, Sagor Kumar Roy   +2 more
wiley   +1 more source

Massive Valproic Acid Overdose With Confirmed Pharmacobezoar Formation and Neuromuscular Toxicity: A Case Report and Literature Review. [PDF]

Cureus
Alrazooqi MK, Abumuaileq L, Zia S, Kazim S.   +3 more
europepmc   +1 more source