Results 151 to 160 of about 74,623 (302)

Early response rates with adjunctive cenobamate in uncontrolled focal seizures: Prospective analysis of a randomized, double‐blind, placebo‐controlled study in a multinational Asian population

open access: yesEpilepsia, EarlyView.
Graphical representation of article highlights, including early response rates with adjunctive cenobamate. Abstract Objective To examine early responses to cenobamate therapy using prospective data from a dose–response study in Asian patients with focal seizures (YKP3089C035, C035) that employed a titration regimen starting at 12.5 mg/day.
Kensuke Kawai   +19 more
wiley   +1 more source

Serum carnitine, beta-hydroxybutyrate and ammonia levels during valproic acid therapy

open access: yesThe Turkish Journal of Pediatrics, 1995
This study was performed in order to determine the effects of valproic acid on serum free carnitine, beta-hydroxybutyrate and blood amamonia.
H B Toksoy, F N Tanzer, A Atalay
doaj  

Clinical trajectories and medication response in TBC1D24‐related epilepsies

open access: yesEpilepsia, EarlyView.
Abstract Objective Biallelic variants in TBC1D24 represent a rare cause of epilepsy and neurodevelopmental disorders, including severe developmental and epileptic encephalopathies. Here, we present the first attempt to delineate the longitudinal disease histories and effectiveness of antiseizure medications (ASMs) in TBC1D24‐related disorders.
Ealing Mondragon   +9 more
wiley   +1 more source

Valproic Acid

open access: yesNew England Journal of Medicine, 1980
openaire   +2 more sources

Treatment approaches in posthypoxic myoclonus: A narrative review with expert opinion

open access: yesEpilepsia, EarlyView.
Abstract Acute posthypoxic myoclonus (PHM) is a neurological complication that typically emerges within 12–48 h following cardiac arrest, often in comatose patients. It can present as generalized, multifocal, or focal myoclonus and has traditionally been associated with poor prognosis.
Marina Romozzi   +7 more
wiley   +1 more source

EHD4 and ASAP2 are critical negative regulators of the claudin‐5‐based endothelial barrier

open access: yesThe FEBS Journal, EarlyView.
Cell‐surface CLDN‐5 protein levels can be evaluated using a probe that can bind to the extracellular domains of CLDN‐5. A probe derived from Clostridium perfringens enterotoxin allows us to isolate cells with high CLDN‐5 protein levels from a knockout cell library.
Yosuke Hashimoto   +8 more
wiley   +1 more source

Reasons for patient reluctance to take preventive medications for migraine: Results of the OVERCOME (US) study

open access: yesHeadache: The Journal of Head and Face Pain, EarlyView.
Abstract Objectives/Background This study was undertaken to evaluate patient reasons for nonadoption of migraine‐preventive medications. Despite clear recommendations and eligibility criteria for migraine‐preventive treatment by the American Headache Society and the availability of these treatments, many people with migraine are not taking appropriate ...
Jessica Ailani   +9 more
wiley   +1 more source

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