Results 181 to 190 of about 74,623 (302)

The Risk Factors and Mortality Among Patients With Different Combination Patterns of Opioids and Benzodiazepines: A Retrospective Study

Pharmacology Research &Perspectives, Volume 14, Issue 1, February 2026.
ABSTRACT The concurrent use of opioids and benzodiazepines (BZDs) has raised safety concerns due to increased risks of respiratory depression and death. To evaluate mortality risks linked to different patterns of co‐prescription, we conducted a retrospective cohort study using data from a private hospital system between 2008 and 2018.
Fang‐Yu Su, Ming‐Che Tsai, Yee‐Yung Ng, Shiao‐Chi Wu   +3 more
wiley   +1 more source

COST OF ILLNESS ANALYSIS OF EPILEPSY OUTPATIENTS USING VALPROIC ACID, PHENYTOIN AND CARBAMAZEPINE THERAPY IN HOSPITAL IN INDONESIA

Adi Nurmesa, Dimas Setyadi Putra, Abu Rachman, Wahyudi Wahyudi   +3 more
openalex   +2 more sources

A QSP Model of Valproic Acid Toxicity in Pediatric and Adult Populations: Implications for Formulation Selection and L‐Carnitine Supplementation

CPT: Pharmacometrics &Systems Pharmacology, Volume 15, Issue 2, February 2026.
Schematic workflow of the QSP model development and application. The study builds upon an initial adult male model structure (top left) by integrating reported data on age‐related changes in elimination pathways (top right). This allowed for the extension of the QSP model to pediatric and female populations (bottom right), which was then used to ...
Alejandra Schiavo, Cecilia Maldonado, Marta Vázquez, Pietro Fagiolino, Inaki F. Trocóniz, Manuel Ibarra   +5 more
wiley   +1 more source

Molecular Investigation of the Effects of Two Antiepileptic Drugs (Valproic Acid and Levetiracetam) on Alveolar Bone Under Orthodontic Force. [PDF]

Medicina (Kaunas)
Bayindir-Durna N, Uckan M, Aydin S, Ozdemir S.   +3 more
europepmc   +1 more source

Supplementary Figure Legends from The Combination of Metformin and Valproic Acid Induces Synergistic Apoptosis in the Presence of p53 and Androgen Signaling in Prostate Cancer

, 2023
Linh Tran, Ganessan Kichenadasse, Lisa M. Butler, Margaret M. Centenera, Katherine L. Morel, Rebecca J. Ormsby, Michael Michael, Karen M. Lower, Pamela J. Sykes   +8 more
openalex   +1 more source

A Novel Human Cellular System for Studying Normal Aging and for Anti‐Aging Discovery

Aging Cell, Volume 25, Issue 2, February 2026.
This study introduces a human cellular aging model using placental trophoblasts (hTSC‐STBs) that mimics key aging features like senescence and genomic instability. It aligns with human tissue aging and responds to anti‐aging treatments, offering a scalable platform to screen potential therapies and bridge lab findings to clinical applications ...
Zhen Feng, Cheuk Shuen Li, Haifeng Fu, Wenxin Jiang, Weiyu Zhang, Yingzhang Huang, Yunying Huang, Timothy Theodore Ka Ki Tam, Yang Li, Fang Liu, Liming Lu, Yin Lau Lee, William Shu Biu Yeung, Gordon Dougan, Pentao Liu   +14 more
wiley   +1 more source

Therapeutic timing limitations of postnatal darbepoetin in a valproic acid rat model of Autism Spectrum Disorder. [PDF]

PLoS One
İpek ÖY, Kirboğa T, Babur E, Dursun N, Süer C.   +4 more
europepmc   +1 more source

The Influence of Health Literacy on the Control of Hypothyroidism in Patients Under Levothyroxine Treatment

Clinical Endocrinology, Volume 104, Issue 2, Page 167-174, February 2026.
ABSTRACT Objective To investigate the association between health literacy levels and biochemical control of hypothyroidism, measured by serum TSH and free thyroxine (FT4) levels, in patients receiving levothyroxine (L‐T4) therapy. Methods We conducted a cross‐sectional study at the Thyroid Disorders Outpatient Clinic, Escola Paulista de Medicina ...
Jessyka Krause Meneses, Daniella Araujo Muniz, Débora Moroto, João Roberto Maciel Martins, Carolina Castro Porto Silva Janovsky   +4 more
wiley   +1 more source

Maternal Immune Stimulation With Interferon-Gamma Limits Embryonic Valproic Acid Induced Apoptotic Gene Expression. [PDF]

Birth Defects Res
Frascella D, Mallela MK, Cullen R, Hrubec TC.   +3 more
europepmc   +1 more source

Data from Valproic acid causes dose- and time-dependent changes in nuclear structure in prostate cancer cells <i>in vitro</i> and <i>in vivo</i>

, 2023
Madeleine S.Q. Kortenhorst, Sumit Isharwal, P. J. van Diest, Wasim H. Chowdhury, Cameron Marlow, Michael A. Carducci, Ronald Rodríguez, Robert W. Veltri   +7 more
openalex   +1 more source