Results 181 to 190 of about 5,054,451 (380)
Abstract Objective Large language models (LLMs) have recently gained attention for clinical decision‐making and diagnosis. This study evaluates the performance of the recently updated LLM Chat Generative Pre‐Trained Transformer‐4omni (ChatGPT‐4o) in predicting clinical outcomes in patients with status epilepticus and compares its prognostic performance
Simon A. Amacher+10 more
wiley +1 more source
VALPROIC ACID PROTECTS KIDNEYS FROM CISPLATIN [PDF]
Cisplatin treatment is effective against several types of carcinomas. However, it frequently leads to kidney injury, which warrants effective prevention methods.
Aizawa, Fuka+13 more
core
Fragile X Syndrome (FXS) is a genetic disease due to a CGG trinucleotide expansion, named full mutation (greater than 200 CGG repeats), in the fragile X mental retardation 1 gene locus Xq27.3; which leads to an hypermethylated region in the gene promoter
Ayala-Zapata, Sebastián+5 more
core +1 more source
Effects of serum albumin and age on free levels of valproic acid in epileptic patients.
Masaru Kawai, SIDO GOSHIMA, YUKIO KITO
openalex +2 more sources
SCN1A pathogenic variants do not have a distinctive blood‐derived DNA methylation signature
Abstract DNA methylation signatures (“episignatures”) can be used as biomarkers of genetic aberrations, clinical phenotypes, and environmental exposures in rare diseases. Episignatures are utilized in molecular diagnostics and can clarify variants of uncertain significance. A growing number of disease genes, including epilepsy genes, exhibit robust and
Christy W. LaFlamme+14 more
wiley +1 more source
Serum carnitine, beta-hydroxybutyrate and ammonia levels during valproic acid therapy
This study was performed in order to determine the effects of valproic acid on serum free carnitine, beta-hydroxybutyrate and blood amamonia.
H B Toksoy, F N Tanzer, A Atalay
doaj
Abstract Objective The aim of the study is to provide insight into the real‐world use of therapeutic drug monitoring (TDM) for the most common antiseizure medications (ASMs). Methods In total, 137 586 samples from the period 2019–2023 were collected from the five main Danish laboratories performing TDM.
Mariam Nersesjan+10 more
wiley +1 more source
Possible teratogenic effect of valproic acid
Susan Clay, Robert McVie, Harold Chen
openalex +1 more source
Valproic acid-associated pancreatitis: report of three cases and a brief review [PDF]
John Lott+4 more
openalex +1 more source
Abstract Objective The aim of this study was to compare the risk of seizure, recurrent stroke, fall or fracture, and mortality in individuals prescribed different antiseizure medications (ASMs) following an ischemic stroke. Methods We identified all patients admitted to a Victorian public or private hospital with a principal diagnosis of an incident ...
Stella Jung‐Hyun Kim+4 more
wiley +1 more source