Results 141 to 150 of about 20,820,978 (349)

Herpes Zoster Risk Among US Cancer Patients Following Initiation of Immunosuppressive Therapy

open access: yesCancer Management and Research
Justin Gatwood,1 Yong Zhu,2 Andrea Steffens,2 Stephanie J Gallagher,2 Mary C DuCharme,2 Kristin J Moore,2 Nikita Stempniewicz1 1GSK, Philadelphia, PA, USA; 2Value and Evidence Solutions, Optum Life Sciences, Eden Prairie, MN, USACorrespondence: Justin ...
Gatwood J   +6 more
doaj  

Ableitung von schichtbezogenen MAK‐Werten für Stäube aus Langzeitgrenzwerten [MAK Value Documentation in German language, 1996] [PDF]

open access: gold, 2012
Deutsche Forschungsgemeinschaft. Ständige Senatskommission zur Prüfung Gesundheitsschädlicher Arbeitsstoffe   +1 more
openalex   +1 more source

Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells

open access: yesFEBS Letters, EarlyView.
Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López   +2 more
wiley   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

A Method for Adjusting EQ-5D-3L Health State Utilities for Cross-Country Use: Application of a Novel US-to-UK Utility Mapping Approach

open access: yesClinicoEconomics and Outcomes Research
Abdul Jabbar Omar Alsaleh,1 Jerome Msihid,2 Elisheva Lew,3 Charlie Nicholls4 1Health Economics and Value Assessment, Sanofi, Milan, Italy; 2Health Economics and Value Assessment, Sanofi, Gentilly, France; 3Health Economics and Value Assessment, Sanofi ...
Omar Alsaleh AJ   +3 more
doaj  

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

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