Results 131 to 140 of about 6,324,451 (244)

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

Evaluation of Bone Healing After Enucleation of Jaw Cysts Using Region of Interest (ROI)-Based Gray Value Analysis on Panoramic Radiographs: A Retrospective Study. [PDF]

Cureus
Durmus HI, Solmaz Ü, Kusan KF, Kizilseki T, Dag N.   +4 more
europepmc   +1 more source

Smaller is better: nanobodies meet NMR

FEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

Residue-Specific Dock-Loosen-Unfold Mechanism of GB1 on Nanoparticle Surfaces Revealed by Kinetic and Φ-Value Analysis. [PDF]

Biomolecules
Liu T, Bian Y, Wang S, Li Y, Cao Y, Jiao Y, Pan H.   +6 more
europepmc   +1 more source

Invisible but not inaccessible—Revealing transient oligomers formed by intrinsically disordered proteins with solution NMR and complementary methods

FEBS Letters, EarlyView.
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley   +1 more source

Clinical value analysis of long non-coding RNA PVT1 in the diagnosis and prognosis, of acute myocardial infarction with arrhythmia. [PDF]

J Cardiothorac Surg
Wang D, Fan L, Wang L, Chen J.
europepmc   +1 more source

Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research

FEBS Letters, EarlyView.
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley   +1 more source

Φ value analysis underscores strong functional and structural compactness of the GABA_A receptor. [PDF]

Proc Natl Acad Sci U S A
Michałowski MA, Terejko K, Gos M, Iżykowska I, Czyżewska MM, Kłopotowski K, Kaczor PT, Brzóstowicz A, Płużek E, Migdałek M, Mozrzymas JW.   +10 more
europepmc   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

Value analysis of preoperative NRS2002 and GLIM screening in predicting postoperative complications in patients with gastrointestinal malignancies. [PDF]

Front Nutr
Xu D, Yan H, Wang J, Zheng P.
europepmc   +1 more source