Results 141 to 150 of about 6,102,456 (244)

Bone mineral density assessment according to Italian essential assistance levels: a positive predictive value analysis based on administrative data. [PDF]

Front Endocrinol (Lausanne)
Abate V, Vergatti A, Cavati G, Magelli S, Varriale A, Merlotti D, De Filippo G, Piccinocchi G, D'Elia L, Gennari L, Rendina D.   +10 more
europepmc   +1 more source

Retracted: Value Analysis of Neoadjuvant Radiotherapy for Breast Cancer after Modified Radical Mastectomy Based on Data Mining. [PDF]

Comput Intell Neurosci, 2023
Intelligence And Neuroscience C.
europepmc   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Association and predictive value analysis for mobility assessments and concerns about falling on falls in community-dwelling older adults: a prospective cohort study in China. [PDF]

BMC Geriatr
Lin J, Guo L, You L, Li N, Zhong J, Zhao M.   +5 more
europepmc   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

The mechanism of amyloid fibril growth from Φ-value analysis. [PDF]

Nat Chem
Larsen JA, Barclay A, Vettore N, Klausen LK, Mangels LN, Coden A, Schmit JD, Lindorff-Larsen K, Buell AK.   +8 more
europepmc   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Predictive value analysis of diaphragmatic ultrasound evaluation for mechanical ventilation outcomes in patients with acute exacerbation of chronic obstructive pulmonary disease. [PDF]

BMC Pulm Med
Qu L, Zhao W, Zhang W, Li J.
europepmc   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

An extreme value analysis of daily new cases of COVID-19 in Africa. [PDF]

Front Public Health
Nadarajah S, Umar AA.
europepmc   +1 more source