Results 101 to 110 of about 3,866,137 (303)

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

Improvement of the physicochemical and mechanical properties of intelligent gelatin/butterfly pea films using coconut milk residue

Applied Food Research
This research investigated the effects of coconut milk residue protein concentrate (CRPC) incorporation (0–3 % w/w) on the properties of gelatin-based films containing butterfly pea extract.
Niramol Punbusayakul, Chalalai Jaisan, Pimonpan Kaewprachu, Suthasinee Yarnpakdee, Yasinee Chakrabandhu   +4 more
doaj   +1 more source

Value chain governance [PDF]

, 2009
This document reports on the discussions during the dinner event held in November 2008. We believe that these discussions and the conversations with the co-applicants set clear directions for next phases of this project.
Helmsing, A.H.J. (Bert), Vellema, S.R. (Sietze)   +1 more
core  

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

Molecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns, Jaclyn S. Long, Sergio Lilla, Kelly Hodge, Marcus J. G. W. Ladds, Colin Nixon, Paula Fernández‐Palanca, Sara Zanivan, Pilar Acedo, Stephen P. Pereira, Kevin M. Ryan   +10 more
wiley   +1 more source

Implication of Digital Marketing in the Supply Chain Finance of the Beverage Industry

International Journal of Financial Studies
This paper investigates the role of digital marketing signals as alternative data for understanding financial and operational dynamics in the beverage supply chain. Drawing on web analytics covering multiple actors across a five-month horizon, we analyze
Nikolaos T. Giannakopoulos, Damianos P. Sakas, Kanellos Toudas, Panagiotis Karountzos   +3 more
doaj   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Harnessing Digital Marketing Analytics for Knowledge-Driven Digital Transformation in the Hospitality Industry

Information
In the digitally saturated hospitality environment, research on digital transformation remains dominated by macro-level adoption trends and user-generated content, while the potential of micro-level web-behavioural data remains largely untapped.
Dimitrios P. Reklitis, Marina C. Terzi, Damianos P. Sakas, Panagiotis Reklitis   +3 more
doaj   +1 more source

Rice Value Chain : a Structuration Theory Approach [PDF]

, 2011
The value chains of rice has created a significant impact in the domestic rice price as well as in Indonesia. As we know from many literatures that providing rice product in time and at different places in the market is very important, especially in ...
Pawitan, G. (Gandhi), Widyarini, M. (Maria)   +1 more
core  

Macroscopic detection of the strong stochasticity threshold in Fermi-Pasta-Ulam chains of oscillators

, 2004
The largest Lyapunov exponent of a system composed by a heavy impurity embedded in a chain of anharmonic nearest-neighbor Fermi-Pasta-Ulam oscillators is numerically computed for various values of the impurity mass $M$.
F. Cecconi, G. Benettin, G. W. Ford, H. Kantz, J. Barré, J. R. Dorfman, L. Casetti, L. Casetti, L. Casetti, M. Romero-Bastida, P. Mazur, R. J. Rubin, R. J. Rubin, R. Livi   +13 more
core   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source