Results 111 to 120 of about 3,828,385 (300)

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

Structural characterization and antibacterial activity of pearl oyster (Pinctada maxima) shell as affected by calcination temperature

open access: yesJournal of Agriculture and Food Research
The effect of calcination temperatures (700, 900 and 1100 °C for 5 h) on structural characteristic and antibacterial activity of calcined pearl oyster (Pinctada maxima) shell were investigated. Yield of calcined powders (CP) were found in the range of 54.
Suthasinee Yarnpakdee   +4 more
doaj   +1 more source

The information value chain: emerging models for procuring electronic publications [PDF]

open access: yes, 2000
The first part of this paper examines the information supply chain and some of its concepts; particular attention is paid to features differentiating electronic from printed information. The second part discusses the procurement process and, in the light
Ball, David, Wright, Susan
core  

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

open access: yesMolecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala   +15 more
wiley   +1 more source

Supply chain integration in New Zealand: benchmark comparisons with the UK automotive sector [PDF]

open access: yes, 2010
Supply chain integration is a promising approach to cross-enterprise process improvement that is still not well understood. This research investigates the level of sophistication (maturity) of supply chain integration in New Zealand from the systems ...
Böhme, Tillmann   +3 more
core   +2 more sources

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

open access: yesMolecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang   +3 more
wiley   +1 more source

Stochastically Perturbed Chains of Variable Memory [PDF]

open access: yes, 2013
In this paper, we study inference for chains of variable order under two distinct contamination regimes. Consider we have a chain of variable memory on a finite alphabet containing zero.
Garcia, Nancy L., Moreira, Lucas
core  

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

Prospects for a certified mint supply chain in Morocco based on an assessment of consumers' willingness to pay [PDF]

open access: yes, 2017
In Morocco, there is a weak control of the quality of fruits and vegetables on the domestic market. The present study assesses the prospects for a certified mint value chain (either complying with legal criteria of maximum residue level or using organic ...
Ait El Mekki, Abdelkader   +3 more
core  

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Home - About - Disclaimer - Privacy