Results 31 to 40 of about 201,185 (264)
Therapeutic Apheresis and Dialysis, EarlyView.ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo +5 more
wiley +1 more source
Therapeutic Apheresis and Dialysis, EarlyView.ABSTRACT Introduction Peritoneal dialysis (PD) is an established home‐based kidney replacement therapy (KRT), but its uptake remains low in Japan. We evaluated whether individualized education in a dedicated outpatient clinic was associated with the initiation of PD.
Yasuko Ito +7 more
wiley +1 more source
Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
BMC GeriatricsBackground The use of diapers among older adults is increasing in aging societies. However, the optimal method of wearing them remains unknown. We aimed to explore procedural variations in leg-through motion during diaper wearing in older adults. Methods
Soichiro Koyama +5 more
doaj +1 more source
The Power of Co-Creation in the Energy Transition—DART Model in Citizen Energy Communities Projects
Energies, 2021 Successful energy transformation is interconnected with greater citizenry participation as prosumers. The search for novel solutions to implement the transition to renewable energy that will neutralize the barriers to this process, e.g., the reluctance ...
Bożena Ryszawska +4 more
doaj +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Journal of Translational Medicine(Background) CD47 is highly expressed on many cancer cells and acts as an innate immune checkpoint. Its binding to signal regulatory protein alpha (SIRPα) on macrophages enables cancer cells to evade phagocytosis.
Yu-Tung Chen +12 more
doaj +1 more source
Co-destruction of Value - A Stakeholder Conceptual Review
International Journal of Business Science and Applied Management, 2022 Co-destruction of value has been highlighted as a possible outcome of every interaction between firms and consumers. Despite the likelihood of its occurrence, the concept is not adequately defined or understood, while little is known about how and where ...
Ogunbodede, O.
doaj
Implications of value co-creation in agro-industrial services
International Journal of Innovation, 2023 Purpose: This study aims to list the managerial implications arisen from an interaction between a brewery and a Brazilian government agency grounded in the Lean principles of value co-creation through a case study.
Fabio Rafael Domiciano Borota +2 more
doaj +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source