Results 51 to 60 of about 4,902,162 (302)

Function‐driven design of a surrogate interleukin‐2 receptor ligand

open access: yesFEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang   +9 more
wiley   +1 more source

The Conceptual Integration of Quality Function Deployment and Value Engineering for Product Development: A Case Study of Water Dispenser

open access: yesInternational Journal of Technology
Nowadays, product development is crucial for ensuring the survival of products in the market. This article focuses on the redesign of water dispenser products based on consumer problems and desires.
Rosnani Ginting   +2 more
doaj   +1 more source

Learning style preference and critical thinking perception among engineering students [PDF]

open access: yes, 2018
Engineering education plays a vital role towards modernization of world. Therefore, engineering students need to be nurture with multiple skills like learning preferences and critical thinking skills.
Muhammad Ismail Jamali, Ali Raza Jamali
core  

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Systematic Review of Value Engineering Research Studies In Indonesia

open access: yesCSID Journal of Infrastructure Development, 2019
Value engineering (VE) plays a significant role in improving project competitiveness and propose an alternative solution to create added value for a project.
Perdana Miraj   +4 more
doaj   +1 more source

Value Engineering Approach for Construction Materials Selection of Irrigation Drainage [PDF]

open access: yes, 2018
In this globalization era, many alternative choices of construction materials. The limited funds available make engineers have to think creatively to choose materials used in order to obtain the cost as efficiently as possible.
Sudiarsa, M. (Made)   +2 more
core  

Mapping customer needs to engineering characteristics: an aerospace perspective for conceptual design

open access: yes, 2014
Designing complex engineering systems, such as an aircraft or an aero-engine, is immensely challenging. Formal Systems Engineering (SE) practices are widely used in the aerospace industry throughout the overall design process to minimise the overall ...
Bertoni, M.   +3 more
core   +3 more sources

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Risk Analysis on Conceptual Design of Soekarno – Hatta International Airport Rail Link Project Using Value Engineering

open access: yesCSID Journal of Infrastructure Development, 2018
The Soekarno-Hatta International Airport Rail Link (SHIARL) project is arguably one of the best solutions to reduce uncertainty in travel time and to improve accessibility to and from Soekarno-Hatta International Airport.
Herawati Z. Rahman   +4 more
doaj   +1 more source

Key success factors analysis for improving cost performance of green retrofit infrastructure on the jetty project

open access: yesJurnal Ilmiah SINERGI, 2023
Several rating definitions must be met following the envision's system. The envisioned system aims to develop the green building concept in the existing jetty building.
Ato Muhan Iswidyantara   +1 more
doaj   +1 more source

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