Results 131 to 140 of about 8,676,945 (352)

Anti-Melanogenic Effects of Takifugu flavidus Muscle Hydrolysate in B16F10 Melanoma Cells and Zebrafish

Marine Drugs
Abnormal melanogenesis can lead to hyperpigmentation. Tyrosinase (TYR), a key rate-limiting enzyme in melanin production, is an important therapeutic target for these disorders.
Jinjin Hu, Bei Chen, Shuaijie Qu, Shuji Liu, Xiaoyu Yang, Kun Qiao, Yongchang Su, Zhihui Liu, Xiaoe Chen, Zhiyu Liu, Qin Wang   +10 more
doaj   +1 more source

Gas diffusion liquid storage bag and method of use for storing blood [PDF]

, 1979
The shelf life of stored whole blood may be doubled by adding a buffer which maintains a desired pH level. However, this buffer causes the generation of CO2 which, if not removed at a controlled rate, causes the pH value of the blood to decrease, which ...
Bank, H., Cleland, E. L.
core   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Education styles in a family versus life aims and values preferred by young people [PDF]

, 2016
Małgorzata Dubis
openalex   +1 more source

Substrate specificity of Burkholderia pseudomallei multidrug transporters is influenced by the hydrophilic patch in the substrate‐binding pocket

FEBS Letters, EarlyView.
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley   +1 more source

Decoding the complete organelle genomic architecture of Stewartia gemmata: an early-diverging species in Theaceae

BMC Genomics
Background Theaceae, comprising 300 + species, holds significance in biodiversity, economics, and culture, notably including the globally consumed tea plant.
Daliang Liu, Zhihan Zhang, Yanlin Hao, Mengge Li, Houlin Yu, Xingruo Zhang, Haoyang Mi, Lin Cheng, Yiyong Zhao   +8 more
doaj   +1 more source

Supplemental Material for Work Preferences, Life Values, and Personal Views of Top Math/Science Graduate Students and the Profoundly Gifted: Developmental Changes and Gender Differences During Emerging Adulthood and Parenthood [PDF]

, 2009
Kimberley Ferriman, David Lubinski, Camilla Persson Benbow   +2 more
openalex   +1 more source

Does the value of quality of life depend on duration? [PDF]

, 2009
The aims of this study are to investigate the feasibility of eliciting Time Trade Off (TTO) valuations using short durations; to determine the effect of contrasting durations on individuals’ responses to the TTO; to examine variations within and between ...
Buckingham, K., Devlin, N., Tilling, C., Tsuchiya, A.   +3 more
core  

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

Wartość własnej śmierci [The value of one’s own death] [PDF]

Analiza i Egzystencja, 2015
In the article I defend the view that nobody can appraise the value of his own death.
Mirosław Rutkowski
doaj