Results 61 to 70 of about 2,685,828 (313)
FEBS Letters, EarlyView.Three‐dimensional (3D) biological systems have become key tools in lymphoma research, offering reliable in vitro and ex vivo platforms to explore pathogenesis and support precision medicine. This review highlights current 3D non‐Hodgkin lymphoma models, detailing their features, advantages, and limitations, and provides a broad perspective on future ...
Carla Faria +3 more
wiley +1 more source
Shiyan dongwu yu bijiao yixueEthical review of animal experiments is based on factors such as the necessity of the experiment, its scientific validity, the professional competence of the experimenters, and research conditions, to determine the ethical permissibility of an animal ...
ZHAO Yong
doaj +1 more source
From omics to AI—mapping the pathogenic pathways in type 2 diabetes
FEBS Letters, EarlyView.Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan +2 more
wiley +1 more source
Medicine Anthropology TheoryPrecision medicine is a field of future promise. Its imaginary is that ‘health data saves lives’. But which lives and at what costs? In this position piece, we direct attention to how non-imagination (Prainsack 2022) operates in the field of precision ...
Mette N. Svendsen, Olivia Spalletta
doaj +1 more source
THE NATURAL-LEGAL DIMENSION OF A PERSON’S STATUS [PDF]
Электронное приложение к Российскому юридическому журналу, 2019 The natural law theory of a person as a substance of his own is presented in the article. The author analyzes historical and contemporary theories and states that any human rights and freedoms can be derived only from such a fundamental level, that a ...
Píry Martin
doaj
FEBS Letters, EarlyView.Knowing how proteases recognise preferred substrates facilitates matching proteases to applications. The S1′ pocket of protease EA1 directs cleavage to the N‐terminal side of hydrophobic residues, particularly leucine. The S1′ pocket of thermolysin differs from EA's at only one position (leucine in place of phenylalanine), which decreases cleavage ...
Grant R. Broomfield +3 more
wiley +1 more source
Evaluation of Suicide in Nursing Students from The Perspective of Meaning of Life and Hope
Journal of NursologyObjective: This study was conducted to determine the effect of meaning in life and hope on suicide probability in nursing students.Methods: A descriptive and correlational design was used.
Gülcan Kendirkıran +2 more
doaj +1 more source
Cognitive Predictors of the Value of One’s Own Life in Students
Проблеми сучасної психології, 2020 The aim of the article is to present the findings of the empirical research on the feeling of the value of one’s own life (VOL) in students. Experiencing the feeling of VOL is understood to be the intended activity of an individual through which they ...
Marat Kuznietsov, Nabil Diab
doaj +1 more source
Exploring lipid diversity and minimalism to define membrane requirements for synthetic cells
FEBS Letters, EarlyView.Designing the lipid membrane of synthetic cells is a complex task, in which its various roles (among them solute transport, membrane protein support, and self‐replication) should all be integrated. In this review, we report the latest top‐down and bottom‐up advances and discuss compatibility and complexity issues of current engineering approaches ...
Sergiy Gan +2 more
wiley +1 more source
FEBS Letters, EarlyView.C‐mannosylation is a unique form of protein glycosylation. In this study, we demonstrated that ADAMTS1 is C‐mannosylated at Trp562 and Trp565 in human testicular germ cell tumor NEC8 cells. We found that C‐mannosylation of ADAMTS1 is essential for its secretion, processing, enzymatic activity, and ability to promote vasculogenic mimicry. These findings
Takato Kobayashi +5 more
wiley +1 more source