Results 71 to 80 of about 166,553,224 (247)
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Age Variations in Workers' Value of Statistical Life [PDF]
This paper develops a life-cycle model in which workers choose both consumption levels and job fatality risks, implying that the effect of age on the value of life is ambiguous.
Joseph E. Aldy, W. Kip Viscusi
core
11th International Conference on Biosystems Engineering 2020 : Book of abstracts : May 6-8 2020 in Tartu, Estonia [PDF]
, 2020 Book of Abstracts. 11th International Conference on Biosystems Engineering 2020, May 6–8, 2020 Tartu, Estonia.
Estonian University of Life Sciences
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The Monetary Value of Human Life Losses Associated with COVID-19 in Africa: A Human Capital Approach
EconomiesBackground: By 30 June 2021, the 54 African sovereign nations had reported 5,465,790 laboratory-confirmed COVID-19 cases (including 142,171 deaths). This study aimed to estimate the monetary value of human life losses, indirect and direct costs, and the ...
Joses Muthuri Kirigia, Germano Mwabu
doaj +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Proceedings of the X International Crane Conference : [21–27 August 2023, Tartu, Estonia] [PDF]
, 2023 We warmly welcome you to Tartu for the X International Crane Conference, hosted by the Estonian University of Life Sciences and organised in cooperation with the European Crane Working Group and the International Crane Foundation.
Estonian University of Life Sciences
core +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Meaning in life and influencing factors among Chinese nurses: a multi-center cross-sectional study
Frontiers in PsychologyBackgroundMeaning in life is a comprehensive understanding of the significance and aim of one's own existence. There is limited research that specifically focuses on meaning in life for nurses, whose work may expose them to substantial workloads ...
Hongli Ma +6 more
doaj +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source