Results 111 to 120 of about 19,210,102 (353)

Economic Burden of Itch-Related Sleep Loss in Moderate-to-Severe Atopic Dermatitis in the United Kingdom

open access: yesDermatology and Therapy
Introduction Atopic dermatitis is associated with intense itch, which has been shown to cause sleep disruption that significantly impacts the lives of patients with atopic dermatitis.
Evangeline J. Pierce   +5 more
doaj   +1 more source

Flow‐based immunomagnetic enrichment of circulating tumor cells from diagnostic leukapheresis product

open access: yesMolecular Oncology, EarlyView.
The number of circulating tumor cells obtained from prostate cancer patients was increased approximately 5‐fold compared to regular CellSearch when processing 2 mL diagnostic leukapheresis material aliquots and increased by 44‐fold when processing 20 mL DLA aliquots using the flow enrichment target capture Halbach‐array.
Michiel Stevens   +8 more
wiley   +1 more source

Key Stakeholders' Value Propositions for Feature Selection in Software-intensive Products: An Industrial Case Study [PDF]

open access: yesarXiv, 2018
Numerous software companies are adopting value-based decision making. However, what does value mean for key stakeholders making decisions? How do different stakeholder groups understand value? Without an explicit understanding of what value means, decisions are subject to ambiguity and vagueness, which are likely to bias them.
arxiv  

Bohr phenomenon for operator valued functions with fixed initial coefficient [PDF]

open access: yesarXiv, 2020
The purpose of this article is to study Bohr inequalities involving the absolute values of the coefficients of an operator valued function. To be more specific, we establish an operator valued analogue of a classical result regarding the Bohr phenomenon for scalar valued functions with fixed initial coefficient.
arxiv  

Unlocking the potential of tumor‐derived DNA in urine for cancer detection: methodological challenges and opportunities

open access: yesMolecular Oncology, EarlyView.
Urine is a rich source of biomarkers for cancer detection. Tumor‐derived material is released into the bloodstream and transported to the urine. Urine can easily be collected from individuals, allowing non‐invasive cancer detection. This review discusses the rationale behind urine‐based cancer detection and its potential for cancer diagnostics ...
Birgit M. M. Wever   +1 more
wiley   +1 more source

Fanaticism and Sacred Values [PDF]

open access: yes, 2019
What, if anything, is fanaticism? Philosophers including Locke, Hume, Shaftesbury, and Kant offered an account of fanaticism, analyzing it as (1) unwavering commitment to an ideal, together with (2) unwillingness to subject the ideal (or its premises ...
Katsafanas, Paul
core   +1 more source

Subpar reporting of pre‐analytical variables in RNA‐focused blood plasma studies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical variables strongly influence the analysis of extracellular RNA (cell‐free RNA; exRNA) derived from blood plasma. Their reporting is essential to allow interpretation and replication of results. By evaluating 200 exRNA studies, we pinpoint a lack of reporting pre‐analytical variables associated with blood collection, plasma preparation ...
Céleste Van Der Schueren   +16 more
wiley   +1 more source

Mind the Value-Action Gap: Do LLMs Act in Alignment with Their Values? [PDF]

open access: yesarXiv
Existing research primarily evaluates the values of LLMs by examining their stated inclinations towards specific values. However, the "Value-Action Gap," a phenomenon rooted in environmental and social psychology, reveals discrepancies between individuals' stated values and their actions in real-world contexts.
arxiv  

Psychometric evaluation of the near activity visual questionnaire presbyopia (NAVQ-P) and additional patient-reported outcome items

open access: yesJournal of Patient-Reported Outcomes
Background The Near Visual Acuity Questionnaire Presbyopia (NAVQ-P) is a patient-reported outcome (PRO) measure that was developed in a phakic presbyopia population to assess near vision function impacts.
Joel Sims   +10 more
doaj   +1 more source

Identification of functional and diverse circulating cancer‐associated fibroblasts in metastatic castration‐naïve prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
Cancer‐associated fibroblasts (CAFs) promote cancer growth, invasion (metastasis), and drug resistance. Here, we identified functional and diverse circulating CAFs (cCAFs) in patients with metastatic prostate cancer (mPCa). cCAFs were found in higher numbers and were functional and diverse in mPCa patients versus healthy individuals, suggesting their ...
Richell Booijink   +6 more
wiley   +1 more source

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