Results 21 to 30 of about 31,154,554 (387)

Patient Experience of Lichen Planus: A Qualitative Exploration of Signs, Symptoms, and Health-Related Quality of Life Impacts

Dermatology and Therapy, 2023
Introduction Lichen planus (LP) is an inflammatory skin disorder that can present in various forms across the body, including lesions on the skin (cutaneous LP [CLP]), scalp (lichen planopilaris [LPP]), and mucosal regions (mucosal LP [MLP]). Qualitative
Aoife Mahon-Smith, Molly Clifford, Anjali Batish, Rosie Sharp, Charlotte Panter, Christel Naujoks, Eva Schruf, Nicolò Compagno, Santiago G. Moreno   +8 more
doaj   +1 more source

Development of symptom-focused outcome measures for advanced and indolent systemic mastocytosis: the AdvSM-SAF and ISM-SAF©

Orphanet Journal of Rare Diseases, 2021
Background Advanced systemic mastocytosis (AdvSM), indolent systemic mastocytosis (ISM), and smoldering systemic mastocytosis (SSM) are rare diseases characterized by neoplastic mast cell infiltration of more than one organ.
Fiona Taylor, Cem Akin, Roger E. Lamoureux, Brad Padilla, Tanya Green, Anthony L. Boral, Iyar Mazar, Brenton Mar, Alan L. Shields, Frank Siebenhaar   +9 more
doaj   +1 more source

Patient-Reported Outcomes in Metastatic Breast Cancer: A Review of Industry-Sponsored Clinical Trials

Breast Cancer: Basic and Clinical Research, 2016
Introduction Patient-reported outcome (PRO) measures serve to capture vital patient information not otherwise obtained by primary study endpoints. This paper examines how PROs are utilized as endpoints in industry-sponsored metastatic breast cancer ...
Meaghan Krohe, Yanni Hao, Roger E. Lamoureux, Nina Galipeau, Denise Globe, Catherine Foley, Iyar Mazar, Jeffrey Solomon, Alan L. Shields   +8 more
doaj   +1 more source

Content validity of the National Comprehensive Cancer Network – Functional Assessment of Cancer Therapy – Breast Cancer Symptom Index (NFBSI-16) and Patient-Reported Outcomes Measurement Information System (PROMIS) Physical Function Short Form with advanced breast cancer patients

Health and Quality of Life Outcomes, 2019
Background The purpose of this study is to evaluate the content validity of the National Comprehensive Cancer Network – Functional Assessment of Cancer Therapy – Breast Cancer Symptom Index (NFBSI-16) and the Patient-Reported Outcomes Measurement ...
Meaghan Krohe, Derek H. Tang, Brittany Klooster, Dennis Revicki, Nina Galipeau, David Cella   +5 more
doaj   +1 more source

Real-world use of ceftolozane/tazobactam: a systematic literature review

Antimicrobial Resistance and Infection Control, 2021
Background Antibacterial-resistant gram-negative infections are a serious risk to global public health. Resistant Enterobacterales and Pseudomonas aeruginosa are highly prevalent, particularly in healthcare settings, and there are limited effective ...
Laura Puzniak, Ryan Dillon, Thomas Palmer, Hannah Collings, Ashley Enstone   +4 more
doaj   +1 more source

Psychometric evaluation of the Indolent Systemic Mastocytosis Symptom Assessment Form (ISM-SAF©) and determination of a threshold score for moderate symptoms

Orphanet Journal of Rare Diseases, 2023
Background The Indolent Systemic Mastocytosis Symptom Assessment Form (ISM-SAF) (©Blueprint Medicines Corporation), a 12-item daily diary that assesses 11 signs and symptoms of indolent systemic mastocytosis (ISM) and smoldering systemic mastocytosis ...
Alan L. Shields, Fiona Taylor, Roger E. Lamoureux, Brad Padilla, Kas Severson, Tanya Green, Anthony L. Boral, Cem Akin, Frank Siebenhaar, Brenton Mar   +9 more
doaj   +1 more source

Content validity of patient-reported outcomes for use in lower-risk myelodysplastic syndromes

Journal of Patient-Reported Outcomes, 2020
Background The lower-risk (low and intermediate-1 risk based on IPSS) myelodysplastic syndrome (MDS) has a negative impact on patients’ health-related quality of life (HRQoL).
Jeremiah J. Trudeau, Jianming He, Esther Rose, Charlotte Panter, Sharan Randhawa, Adam Gater   +5 more
doaj   +1 more source

Assessing asthma symptoms in children: qualitative research supporting the development of the Pediatric Asthma Diary—Child (PAD-C) and Pediatric Asthma Diary—Observer (PAD-O)

Journal of Patient-Reported Outcomes, 2023
Background Pediatric asthma has been identified by regulators, clinicians, clinical trial sponsors, and caregivers as an area in need of novel fit-for-purpose clinical outcome assessments (COAs) developed in accordance with the U.S.
Helena Bradley, Claire Trennery, Amy M. Jones, Aoife Lydon, Frances White, Rebecca Williams-Hall, Rob Arbuckle, Erin Tomaszewski, Vivian H. Shih, John Haughney, Amanda Eisen, Tonya Winders, Stephen Joel Coons, Sonya Eremenco, the Patient-Reported Outcome Consortium’s Pediatric Asthma Working Group   +14 more
doaj   +1 more source

Humans, robots and values [PDF]

, 2016
The issue of machines replacing humans dates back to the dawn of industrialisation. In this paper we examine what is fundamental in the distinction between human and robotic work by reflecting on the work of the classical political economists and ...
Cockshott, Paul, Renaud, Karen
core   +2 more sources

An Overview of the Schwartz Theory of Basic Values

, 2012
This article presents an overview of the Schwartz theory of basic human values. It discusses the nature of values and spells out the features that are common to all values and what distinguishes one value from another.
S. Schwartz
semanticscholar   +1 more source