Results 91 to 100 of about 13,533,448 (310)

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

The Ethics and Moral Values in Digital Education: A Cluster-Based Exploration of Student Perspectives

As digital education continues to expand, ethical concerns such as data privacy, academic integrity, accessibility, ethical awareness, and moral values have become increasingly important.
Seiitkazy, Perizat, Tantakov, Galymzhan, Maigeldiyeva, Sharban, Omarov, Daulet, Maigeldiyeva, Zhannat   +4 more
core   +1 more source

Artificial Intelligence and Training in Values in Higher Education: An Inter-University Study Between Spain and Ireland

Trends in Higher Education
This study examines the role of artificial intelligence (AI) as a mediating tool in values training, based on university students’ reflections on their own values and those represented in literary characters.
José Antonio Ortí Martínez, Esther Puerto Martínez   +1 more
doaj   +1 more source

Evaluation of the Level of Perseverance in Adolescents

Journal of Educational Studies, 2023
The importance of perseverance in students' development and the learning process in today's society is increasingly a subject of thinking and implementation.
Florina Grațiela Șchiopu-Constantin
doaj  

Retracted: An Analysis of Students' Work Values Education Strategies and Environment Based on Psychological Contract. [PDF]

J Environ Public Health, 2023
Environmental And Public Health JO.
europepmc   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Okul Öncesi Eğitimi Öğretmenlerinin Değerler Eğitimi Konusundaki Görüşleri: Denizli İli Örneği

Sakarya Üniversitesi Eğitim Fakültesi Dergisi, 2015
Araştırmanın amacı, okul öncesi eğitimi öğretmenlerinin değerler eğitimi ile ilgili görüşlerini ortaya koymaktır. Araştırmanın çalışma grubunu Denizli il merkezinde Milli Eğitim Bakanlığı’na bağlı anasınıflarında, bağımsız anaokullarında ve uygulama ...
Hatice Sarıkaya, Hülya Gülay Ogelman
doaj  

The axiological dimensions of the Romanian National Curriculum: a qualitative analysis of educational values

Frontiers in Education
This study examines the Romanian National Curriculum from an axiological perspective, in the context of recent normative developments, including the Pre-university Education Law (2023). It aims to explore how democratic, civic, and socio-emotional values
Mona Bădoi-Hammami, Silvia-Raluca Matei, Daniela Căprioară, Carmen Mihaela Băiceanu, Miruna Felicia Moroianu, Claudia-Simona Popa, Monica Moraru, Ana Maria Bezem, Mirela Mihaela Doga, Cristian Petre, Iuliana Lungu   +10 more
doaj   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source