Results 81 to 90 of about 5,082,329 (311)

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

The axiological dimensions of the Romanian National Curriculum: a qualitative analysis of educational values

open access: yesFrontiers in Education
This study examines the Romanian National Curriculum from an axiological perspective, in the context of recent normative developments, including the Pre-university Education Law (2023). It aims to explore how democratic, civic, and socio-emotional values
Mona Bădoi-Hammami   +10 more
doaj   +1 more source

Value-based Curriculum model from the Viewpoints of Experts in Education of Ethics and Values in Shahid Beheshti University of Medical Sciences [PDF]

open access: yesمجله ایرانی آموزش در علوم پزشکی, 2015
Introduction: Knowing and understanding the views of educational program stakeholders, especially faculty members about the concept of value-based curriculum are requirements of appropriate planning in this field.
Shahram Yazdani   +4 more
doaj  

Values Education or Religious Education? An Alternative View of Religious Education in the Secular Age, the Case of Turkey

open access: yesEducation Sciences, 2018
Debates about the teaching of religion date back to the formation of the modern education system, when religion was first compartmentalized as a distinct subject within a broader curriculum. In many places, they continue to rage today.
Muhammet Fatih GENÇ
doaj   +1 more source

Ethics education in Polish schools – a multicultural approach with a global view [PDF]

open access: yes, 2015
Special issue / ENASTEThe aim of this paper is to highlight one of the issues which insufficiently deals with the relationship between globalization, migration and multicultural education: teaching values.
Leek, Joanna
core  

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

Okul Öncesi Eğitimi Öğretmenlerinin Değerler Eğitimi Konusundaki Görüşleri: Denizli İli Örneği

open access: yesSakarya Üniversitesi Eğitim Fakültesi Dergisi, 2015
Araştırmanın amacı, okul öncesi eğitimi öğretmenlerinin değerler eğitimi ile ilgili görüşlerini ortaya koymaktır. Araştırmanın çalışma grubunu Denizli il merkezinde Milli Eğitim Bakanlığı’na bağlı anasınıflarında, bağımsız anaokullarında ve uygulama ...
Hatice Sarıkaya, Hülya Gülay Ogelman
doaj  

Teaching Peace – The Need for Teacher Training in Poland to Promote Peace [PDF]

open access: yes, 2015
The aim of the paper is to stimulate the discussion on peace education and the need of teacher training for peace and multicultural understanding. This paper is organized in two sections: the first section presents the importance of peace education for ...
Leek, Joanna
core  

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

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