Results 101 to 110 of about 5,082,329 (311)
The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity
Molecular Oncology, EarlyView.Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli +7 more
wiley +1 more source
Panta rei, 2018 This paper presents an experience of teaching innovation in didactics of history. The experience was carried out in initial teacher training and was based on the combined use of primary sources and digital resources, with the aim of developing an ...
Nayra Llonch-Molina +1 more
doaj +1 more source
Molecular Oncology, EarlyView.In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source
Технологический и культурный суверенитет России и образование: обзор публикаций
Научно-педагогическое обозрениеМатериалы статьи основаны на анализе публикаций (за период с 2021 по 2025 год), посвященных вопросам достижения культурного и технологического суверенитета страны, а также роли образования в этих вопросах.
Семёнова Наталия Альбертовна +1 more
doaj +1 more source
VaKE(Values and Knowledge Education). Piloting a strategy for NursingEducation [PDF]
, 2017 Nurses are expected to have health responses which imply interdisciplinary, multi-professional dynamics, require high responsibility and consistent general knowledge to deal with many different, very specific patient needs, which lead them to deal with ...
Esteves, Mariana +9 more
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Molecular Oncology, EarlyView.Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source
JAVANESE VIEW ON EDUCATION: AN ETNOLINGUISTIC STUDY [PDF]
, 2013 This is an etnolinguistic study which is aimed to describe the Javanese view on education as reflected on its proverbs. The data of this research were Javanese proverbs dealt with education which were gathered both from literatures and observation ...
Kurniawati, Atin
core
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Molecular Oncology, EarlyView.Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano +6 more
wiley +1 more source