Results 111 to 120 of about 6,778 (229)

Autophagy in MASLD: A Metabolic and Precision Medicine Perspective

open access: yesLiver International, Volume 46, Issue 9, September 2026.
ABSTRACT Metabolic dysfunction‐associated steatotic liver disease (MASLD) is the most common chronic liver condition worldwide and a major contributor to cirrhosis and hepatocellular carcinoma (HCC). While metabolic triggers such as obesity and insulin resistance are key drivers of MASLD, growing evidence has identified defects in intracellular quality
Alessandra Cazzaniga   +4 more
wiley   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

open access: yesMolecular Oncology, Volume 20, Issue 8, Page 1913-1932, August 2026.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain   +10 more
wiley   +1 more source

Synaptic biomarkers in Alzheimer's disease dementia and mild cognitive impairment: A systematic review and meta-analysis. [PDF]

open access: yesAlzheimers Dement
Gaur A   +10 more
europepmc   +1 more source

Acute and Chronic Leukemia in Sub‐Saharan Africa: A Systematic Review

open access: yesCancer Reports, Volume 9, Issue 8, August 2026.
ABSTRACT Background The four primary subgroups of leukemia include chronic myeloid leukemia (CML), acute myeloid leukemia (AML), acute lymphoblastic leukemia (ALL), and chronic lymphocytic leukemia (CLL). Very little is known about the regional variation of leukemia and subtypes in sub‐Saharan Africa (SSA).
Allwell A. Ayirebi   +17 more
wiley   +1 more source

Ameliorating Linguistic Anchors of Oppression

open access: yesJournal of Applied Philosophy, Volume 43, Issue 4, Page 1014-1033, August 2026.
ABSTRACT The words we use to represent the world shape how we interpret and respond to it; language frames what it represents. In some cases, these frames can have prejudicial effects; for example, ‘workplace flirting’ versus ‘sexual harassment’. This article examines how specific words and phrases (i.e.
Emilia L. Wilson
wiley   +1 more source

Task‐Evoked Functional Activation and Coupling With CSF Flow Detected in the Human Brain With Ultrashort Echo Time fMRI at 7 T

open access: yesNMR in Biomedicine, Volume 39, Issue 8, August 2026.
Ultrashort and zero echo time (UTE and ZTE) MRI techniques generate functional contrast through inflow effects, making them suitable for studying cerebral blood flow and cerebrospinal fluid (CSF) dynamics. In a 7‐T study of 13 participants performing a visual task, we demonstrate that UTE produced robust, reproducible activations with group‐level ...
Sara Ponticorvo   +7 more
wiley   +1 more source

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