Aggressive prostate cancer is associated with pericyte dysfunction
Molecular Oncology, EarlyView.Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero +11 more
wiley +1 more source
Van’da Bulunan Osmanlı Vakıfları
Yüzüncü Yıl Üniversitesi Sosyal Bilimler Enstitüsü Dergisi, 2021 Van’ı 1548 yılında tam olarak hâkimiyeti altına alan Osmanlı Devleti şehrin askerî, siyasî, iktisadî, sosyal, kültürel, dinî ve eğitim ihtiyaçlarını karşılamak için çeşitli eserler bina ettirmiştir.
Sami Ağaoğlu
doaj
The Image of the City in Armenia: Anthropological Perspective
Urbis et Orbis: Mikroistoriâ i Semiotika Goroda, 2023 Socially significant phenomena are usually personified and embodied in the images of ancestors, ethnarchs, and heroes. The anthropomorphic symbol in the fine arts was an integral part of ancient Greek culture from the very beginning.
Viktorya Vasilyan
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Perceptions of student price-responsiveness ; a behavioural economics exploration of the relationships between socio-economic status, perceptions of financial incentives and student choice [PDF]
, 2005 Studenten die hoge collegegelden moeten betalen hebben wel leenaversie, maar dit weerhoudt hen er niet van om te gaan studeren of te lenen. In zijn proefschrift Perceptions of Student Price-Responsiveness toont Hans Vossensteyn aan dat de verhogingen van
Vossensteyn, Johan Jacob (Hans)
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Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA
Molecular Oncology, EarlyView.Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson +2 more
wiley +1 more source
MAIN MYTHS RELATED TO THE LAKE VAN BASIN (PRELIMINARY ATTEMPT OF CLASSIFICATION AND TYPOLOGICAL DIFFERENTIATION OF MYTHOLOGICAL NARRATIVES) [PDF]
Banber Arevelagitut'yan Instituti, 2019 As known, geographical environment, climatic conditions stipulate any region’s population’s culture and mythological imagination to a significant extent.
HASMIK HMAYAKYAN
doaj
Sugar quotas: yes or no? : economic consequences for sector, chain, international market situation and third world [PDF]
, 2011 Het ministerie van EL&I heeft het LEI gevraagd inzicht te verschaffen in de argumenten voor en tegen voortzetting van het centrale element van de huidige suikermarktordening, de quotering, na september 2015.
Bont, C.J.A.M., de, Smit, A.B.
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Discussion of "Frequentist coverage of adaptive nonparametric Bayesian credible sets" [PDF]
, 2015 Discussion of "Frequentist coverage of adaptive nonparametric Bayesian credible sets" by Szab\'o, van der Vaart and van Zanten [arXiv:1310.4489v5].Comment: Published at http://dx.doi.org/10.1214/15-AOS1270D in the Annals of Statistics (http://www ...
Low, Mark G., Ma, Zongming
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Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
Lacan’s discourse theory in the age of evidence-based practice [PDF]
, 2006 Deze lezing vergelijkt de hedendaagse empirisch-kwantitatieve benadering omtrent effectiviteit van psychotherapieën met een bestudering van de effecten van psychotherapie aan de hand van de Lacaniaanse discourstheorie.
Desmet, Mattias
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