An outbreak of vanA vancomycin-resistant Enterococcus faecium in a hospital with endemic vanB VRE [PDF]
In Australia, vanB vancomycin-resistant Enterococcus faecium (VREfm) has been endemic for over 20 years, but vanA VREfm isolates have rarely been reported.This outbreak report describes an outbreak of vanA VREfm in the intensive care unit (ICU) and cardiothoracic surgery (CTS) wards of a Melbourne hospital in 2015-2016.
Angus Hughes +3 more
openaire +2 more sources
Enzymatic DNA Reaction Networks for Orchestrating Stimuli‐Dependent Temporal Molecular Pulse
We present an enzymatic DNA reaction network (EDRN) that encodes nucleic‐acid targets in time, converting inputs into a universal strand and then into programmable transient fluorescence pulses. With time‐color multiplexing, EDRN enables single‐tube high‐plex nucleic acid detection and shows strong agreement with clinical sequencing across 32 specimens.
Jiayu Yang +7 more
wiley +1 more source
Comparison of Three PCR Primer Sets for Identification of vanB Gene Carriage in Feces and Correlation with Carriage of Vancomycin-Resistant Enterococci: Interference by vanB -Containing Anaerobic Bacilli [PDF]
ABSTRACT We assessed the sensitivities and specificities of three previously described PCR primers on enrichment broth cultures of feces for the accurate detection of fecal carriage of vancomycin-resistant enterococci (VRE). In addition, we investigated specimens that were vanB PCR positive but VRE culture
S A, Ballard +3 more
openaire +2 more sources
Performic acid (PFA) achieved rapid, linear, and consistent inactivation of enterococci and vancomycin‐resistant enterococci, peracetic acid (PAA) exhibited slower, variable kinetics with distinctive shouldering, and sodium hypochlorite proved the least reliable and displayed a “lower dose advantage.” These findings position PFA as a promising ...
Nuha Alfahham +4 more
wiley +1 more source
Antibiotic Remodeling of the Gut Microbiota Impairs Host Resistance to Secondary Infection
Gut microbial dynamics induced by four antibiotics, revealed distinct taxonomic and functional shifts. Vancomycin‐perturbed bacteriomes were proven to promote pathogen resistance to antibiotic treatment. Metronidazole‐treated mice showed pronounced Salmonella translocation to hepatic tissue, and altered Enterococcus avium populations modulated host ...
Miaoyu Li +17 more
wiley +1 more source
High Rates of Fecal Carriage of Nonenterococcal vanB in both Children and Adults [PDF]
ABSTRACT We examined the rate of fecal carriage of vanB in the absence of cultivable vancomycin-resistant enterococci in three distinct populations (children, community adults, and hemodialysis patients). Nonenterococcal vanB carriage was similarly high in hemodialysis patients (45%)
M, Graham +4 more
openaire +2 more sources
On average, phones harbored 3.62 of the top 10 killers and 2.49 ESKAPE organisms. In total, 667 VFGs (8621 Hits) and 262 ARGs (2475 Hits) were identified on 95 mobile phones. Mobile phones serve as a platform for horizontal gene transfer and AMR development.
Adrian Goldsworthy +12 more
wiley +1 more source
Purification and characterization of the VanB ligase associated with type B vancomycin resistance in Enterococcus faecalis V583 [PDF]
Acquired resistance to glycopeptides in enterococci is associated with the production of D-Alanine: D-Alanine ligase-related proteins. The VanA protein associated with high-level vancomycin and teicoplanin resistance (VanA phenotype) synthesizes a new ...
Stefan Evers +9 more
core +1 more source
Evaluation of FilmArray Multiplex PCR Test Results in Bloodstream Infections in Oncological Patients
In this study conducted at an oncology hospital, BCID2 panel results for the rapid identification of microorganisms and resistance genes in positive blood culture samples were compared with conventional culture methods. The BCID2 panel provided faster results and showed a high correlation with traditional methods.
İpek Mumcuoğlu +6 more
wiley +1 more source
Mechanism of VanB Phenotype in Vancomycin-Resistant Enterococci carrying vanA gene [PDF]
Background: Recently, vancomycin-resistant enterococci (VRE) with the vanA genotype that are susceptible to teicoplanin have been described in Japan, Taiwan, and Korea.
용동은, 이경원
core +1 more source

