Results 121 to 130 of about 252,519 (340)

Engineered Stable, Antibiotic‐Free, High‐Level Protein Expression in the Probiotic Chassis Escherichia coli Nissle 1917

Biotechnology and Bioengineering, EarlyView.
The probiotic E. coli Nissle 1917 was engineered to enable stable and antibiotic free protein expression platforms using native plasmids. Further modification aids in the production of high‐level protein expression for antimicrobial secretion whose activity is comparable to industry standard E. coli BL21.
Halimatun Sakdiah Zainuddin, Sanjeeva Kumar Murali, Thomas J. Mansell   +2 more
wiley   +1 more source

Vancomycin levels are frequently subtherapeutic in critically ill patients: a prospective observational study [PDF]

, 2017
Victoria Désirée Bakke, Hilde Sporsem, E von der Lippe, Ingvild Nordøy, Yvonne Elisabeth Lao, Hans Christian Nyrerød, Leiv Sandvik, K. R. Hårvig, J. F. Bugge, E. Helset   +9 more
openalex   +1 more source

Continuous infusion versus intermittent infusion of vancomycin in critically ill patients undergoing continuous venovenous hemofiltration: A prospective interventional study [PDF]

, 2022
Jinhui Xu, Lufen Duan, Jiahui Li, Fang Chen, Xiaowen Xu, Jian Lü, Zhiwei Zhuang, Yifei Cao, Yunlong Yuan, Xin Liu, Jiantong Sun, Qin Zhou, Lu Shi, Lian Tang   +13 more
openalex   +1 more source

Cystatin C‐based eGFR better predicts renal vancomycin clearance than creatinine‐based eGFR in patients with allogeneic stem cell transplantation

Clinical Pharmacology &Therapeutics, EarlyView.
Knowledge of the glomerular filtration rate (GFR) is mandatory when dosing renally eliminated drugs such as vancomycin. In clinical practice, different biomarkers and various equations are used to estimate GFR (eGFR), resulting in varying estimates.
Eva‐Maria A. Wansing, Sebastian G. Wicha, Peter Bannas, Alexander Heitkamp, Adrin Dadkhah, Nicolaus M. Kröger, Isabel Molwitz, Claudia Langebrake   +7 more
wiley   +1 more source

Risk of Acute Kidney Injury Associated With Nephrotoxic Burden in Hospitalized Patients: A Scoping Review

Clinical Pharmacology &Therapeutics, EarlyView.
Limited evidence exists synthesizing the risk of acute kidney injury (AKI) associated with the concomitant administration of multiple nephrotoxic drugs, and even less examining the concept of nephrotoxic burden. The objective of this scoping review was to (1) identify definitions of nephrotoxic burden; (2) methods used to quantify (use of calculations)
Wafa Alatawi, Jessica L. Wallace, Dhakrit Rungkitwattanakul, Britney A. Stottlemyer, Tiffany L. Tran, Melanie Manis Reida, Sandra L. Kane‐Gill   +6 more
wiley   +1 more source

Estimation of Glomerular Filtration Rate to Adjust Vancomycin Dosage in Critically Ill Patients: Superiority of the Chronic Kidney Disease Epidemiology Collaboration Equation? [PDF]

, 2014
Jean‐Marie Conil, B. Georges, Audrey Breden, Stéphanie Ruiz, P. Cougot, Olivier Fourcade, Sylvie Saivin   +6 more
openalex   +1 more source

RORγt‐APCs: The New Masters of Oral Tolerance

Barrier Immunity, EarlyView.
ABSTRACT Oral tolerance is defined by the hypo‐responsiveness of our body to fed antigens, and its failure can lead to immune‐mediated diseases, such as allergy, chronic inflammation and autoimmune diseases. Decades of research have demonstrated that antigen‐presenting cells (APCs) promote oral tolerance by inducing regulatory T cells (Tregs) and/or ...
Thierry Gauthier, WanJun Chen
wiley   +1 more source

A Genetic Locus in Elizabethkingia anophelis Associated with Elevated Vancomycin Resistance and Multiple Antibiotic Reduced Susceptibility

Antibiotics
The Gram-negative Elizabethkingia express multiple antibiotic resistance and cause severe opportunistic infections. Vancomycin is commonly used to treat Gram-positive infections and has also been used to treat Elizabethkingia infections, even though Gram-
William L. Johnson, Sushim Kumar Gupta, Suman Maharjan, Randy M. Morgenstein, Ainsley C. Nicholson, John R. McQuiston, John E. Gustafson   +6 more
doaj   +1 more source

Recent Developments in Capillary and Microchip Electroseparations of Peptides (2023–mid 2025)

ELECTROPHORESIS, EarlyView.
ABSTRACT This review presents a comprehensive overview of the developments and applications of high‐performance capillary and microchip electromigration methods (zone electrophoresis in a free solution or in sieving media, isotachophoresis, isoelectric focusing, affinity electrophoresis, electrokinetic chromatography, and electrochromatography) for ...
Václav Kašička
wiley   +1 more source

Two Cases of Vancomycin-Induced Neutropenia

Pharmacy
(1) Background: The incidence of vancomycin-induced neutropenia in hospitalized patients is estimated to be around 2 to 8 percent Data surrounding vancomycin-induced neutropenia is limited as it is based on a small number of observational case reports ...
Kirsten Ganaja, Sarah Scoular, Staci Hemmer   +2 more
doaj   +1 more source