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Journal of Antimicrobial Chemotherapy, 1982
While vancomycin is thus not as nephrotoxic as once feared, its use by the parenteral route should be avoided if possible when other nephrotoxic drugs are being given. Used properly, vancomycin appears efficacious and can be given with safety to infants, children, and adults.
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While vancomycin is thus not as nephrotoxic as once feared, its use by the parenteral route should be avoided if possible when other nephrotoxic drugs are being given. Used properly, vancomycin appears efficacious and can be given with safety to infants, children, and adults.
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Mayo Clinic Proceedings, 1987
Vancomycin is a narrow-spectrum bactericidal antibiotic used primarily for treatment of serious staphylococcal infections. It is the alternative therapy of choice when the penicillins and cephalosporins cannot be used. Vancomycin is also used in (1) methicillin-resistant Staphylococcus aureus infections; (2) streptococcal endocarditis in conjunction ...
P E, Hermans, M P, Wilhelm
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Vancomycin is a narrow-spectrum bactericidal antibiotic used primarily for treatment of serious staphylococcal infections. It is the alternative therapy of choice when the penicillins and cephalosporins cannot be used. Vancomycin is also used in (1) methicillin-resistant Staphylococcus aureus infections; (2) streptococcal endocarditis in conjunction ...
P E, Hermans, M P, Wilhelm
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Vancomycin Use in a Hospital With Vancomycin Restriction
Infection Control & Hospital Epidemiology, 1999AbstractWe evaluated vancomycin use in a hospital with endemic vancomycin-resistant enterococci and a vancomycin restriction program. Only 68% of vancomycin was prescribed appropriately. Inappropriate use was due primarily to empirical therapy. In the patients with a microbiological diagnosis following empirical therapy, 83% (25/30) had infections due ...
M C, Roghmann, B E, Perdue, L, Polish
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Annals of Internal Medicine, 1978
Vancomycin, virtually discarded after development of antistaphylococcal penicillins, has recently been receiving renewed attention. There are several clinical situations in which it appears to offer advantages over other available antimicrobial agents: infections due to methicillin-resistant staphylococci; bacterial endocarditis in patients allergic to
F V, Cook, W E, Farrar
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Vancomycin, virtually discarded after development of antistaphylococcal penicillins, has recently been receiving renewed attention. There are several clinical situations in which it appears to offer advantages over other available antimicrobial agents: infections due to methicillin-resistant staphylococci; bacterial endocarditis in patients allergic to
F V, Cook, W E, Farrar
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Mayo Clinic Proceedings, 1991
Vancomycin is a glycopeptide antibiotic that is active against staphylococci, streptococci, and other gram-positive bacteria. It is the drug of choice for the treatment of infections due to methicillin-resistant staphylococci, Corynebacterium jeikeium, and multiply resistant strains of Streptococcus pneumoniae.
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Vancomycin is a glycopeptide antibiotic that is active against staphylococci, streptococci, and other gram-positive bacteria. It is the drug of choice for the treatment of infections due to methicillin-resistant staphylococci, Corynebacterium jeikeium, and multiply resistant strains of Streptococcus pneumoniae.
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Mayo Clinic Proceedings, 1977
Vancomycin, a useful bactericidal antibiotic for selective clinical infections, is the therapy of choice for serious staphylococcal infections when the penicillins and cephalosporins cannot be used. The antibacterial spectrum of vancomycin also covers other gram-positive cocci and bacteria and gram-negative cocci.
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Vancomycin, a useful bactericidal antibiotic for selective clinical infections, is the therapy of choice for serious staphylococcal infections when the penicillins and cephalosporins cannot be used. The antibacterial spectrum of vancomycin also covers other gram-positive cocci and bacteria and gram-negative cocci.
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Chloramphenicol and Vancomycin
Clinics in Laboratory Medicine, 1987These two antibiotics have been important agents in the treatment of serious infections. Chloramphenicol use is decreasing owing to the potentially fatal toxicities associated with its use. Vancomycin use, on the other hand, is increasing owing to the emergence of methicillin-resistant staphylococci.
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Archives of Pediatrics & Adolescent Medicine, 1984
In this issue of the AJDC , Odio et al 1 and Alpert et al 2 report disturbing observations concerning the clinical use of vancomycin hydrochloride. The pharmaceutical formulation of vancomycin has been vastly improved in recent years, and the more uniform preparation has been considered reasonably safe when administered and monitored appropriately ...
W, Banner, C G, Ray
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In this issue of the AJDC , Odio et al 1 and Alpert et al 2 report disturbing observations concerning the clinical use of vancomycin hydrochloride. The pharmaceutical formulation of vancomycin has been vastly improved in recent years, and the more uniform preparation has been considered reasonably safe when administered and monitored appropriately ...
W, Banner, C G, Ray
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Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy, 1986
Vancomycin is a narrow‐spectrum glycopeptide antibiotic with potent antistaphylococcal activity. It is primarily active against gram‐positive organisms. Bacterial resistance rarely develops due to its numerous modes of action. The toxic potential of vancomycin is less significant than previously thought.
R P, Cheung, J T, DiPiro
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Vancomycin is a narrow‐spectrum glycopeptide antibiotic with potent antistaphylococcal activity. It is primarily active against gram‐positive organisms. Bacterial resistance rarely develops due to its numerous modes of action. The toxic potential of vancomycin is less significant than previously thought.
R P, Cheung, J T, DiPiro
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Pharmacokinetics of vancomycin
Journal of Antimicrobial Chemotherapy, 1984Vancomycin is poorly absorbed when administered by mouth and, for systemic infections, must be given intravenously. The pharmacokinetics of vancomycin have been well defined in a number of recent studies in man. Since the drug is excreted primarily via the kidneys, dosage modification is imperative in patients with impaired renal function.
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