Results 121 to 130 of about 165,040 (305)

Offset‐Reducing and Sulcus‐Deepening Trochleoplasty for the Combined Treatment of Patellar Instability and Anterior Knee Pain Using Vicryl Sutures

Arthroscopy Techniques, EarlyView.
Abstract Trochlear dysplasia is one of the most important factors that influences the biomechanics of the patellofemoral (PF) joint. In cases of PF instability, trochlear dysplasia is associated with a significant increase in the risk of redislocation.
Jannik Frings, Armin Runer, Markus T. Berninger, Karl‐Heinz Frosch, Tobias Drenck, Matthias Krause   +5 more
wiley   +1 more source

Oral vancomycin solution is superior to capsule in inducing clinical biomarker and endoscopic remission in children with atypical ulcerative colitis

British Journal of Clinical Pharmacology, EarlyView.
Aims Atypical colitis (presenting reverse gradient colitis, backwash ileitis or rectal sparing) is associated with primary sclerosing cholangitis–ulcerative colitis (PSC). Oral vancomycin has been used to manage paediatric atypical colitis with/without confirmed PSC. Different preparations had shown different efficacy.
Laura Räisänen, Fariha Balouch, Claire Reilly, Christopher Burgess, Peter Lewindon   +4 more
wiley   +1 more source

Low necessity, high overuse: revisiting empirical vancomycin practices for children in low MRSA prevalence settings

BMC Infectious Diseases
Background The overuse of vancomycin as empirical therapy ranged from 62% to 66% worldwide, while the prevalence of proven infections requiring vancomycin was only 11% to 27%.
Phuwakrit Nithirungruang, Chonnamet Techasaensiri, Sophida Boonsathorn, Sujittra Chaisavaneeyakorn, Nopporn Apiwattanakul   +4 more
doaj   +1 more source

A Genetic Locus in Elizabethkingia anophelis Associated with Elevated Vancomycin Resistance and Multiple Antibiotic Reduced Susceptibility

Antibiotics
The Gram-negative Elizabethkingia express multiple antibiotic resistance and cause severe opportunistic infections. Vancomycin is commonly used to treat Gram-positive infections and has also been used to treat Elizabethkingia infections, even though Gram-
William L. Johnson, Sushim Kumar Gupta, Suman Maharjan, Randy M. Morgenstein, Ainsley C. Nicholson, John R. McQuiston, John E. Gustafson   +6 more
doaj   +1 more source

Vancomycin-induced increase in yvcJ and glmR expression is reduced in the ΔyvcL mutant.

RNA was purified from E. faecalis strains grown to exponential phase in MH broth and treated, or not, with 3 μg/ml vancomycin. Expression was measured using RT-qPCR with normalization to 16S rRNA, and fold induction (treated versus untreated) was ...
Christopher J. Kristich (2570176), Dušanka Djorić (16649064), Samantha N. Atkinson (5879318)   +2 more
core   +1 more source

Evaluating and leveraging large language models in clinical pharmacology and therapeutics assessment: From exam takers to exam shapers

British Journal of Clinical Pharmacology, EarlyView.
Aims In medical education, the ability of large language models (LLMs) to match human performance raises questions about their potential as educational tools. This study evaluates LLMs' performance on Clinical Pharmacology and Therapeutics (CPT) exams, comparing their results to medical students and exploring their ability to identify poorly formulated
Alexandre O. Gérard, Diane Merino, Marc Labriffe, Fanny Rocher, Delphine Viard, Laurence Zemori, Thibaud Lavrut, Erik M. Donker, Joost D. Piët, Jean‐Paul Fournier, Milou‐Daniel Drici, Alexandre Destere   +11 more
wiley   +1 more source

The pharmacokinetics of vancomycin during the initial loading dose in patients with septic shock

, 2016
Wasan Katip,1 Sutep Jaruratanasirikul,2 Sutthiporn Pattharachayakul,3 Wibul Wongpoowarak,4 Arnurai Jitsurong,5 Aroonrut Lucksiri1 1Department of Pharmaceutical Care, Faculty of Pharmacy, Chiang Mai University, Chiang Mai, 2Department of Medicine, Faculty
Katip W, Wongpoowarak W, Lucksiri A, Pattharachayakul S, Jitsurong A, Jaruratanasirikul S   +5 more
core  

Systematic review and scoring‐based selection of pharmacokinetic models for precision dosing of vancomycin in neonates and children

British Journal of Clinical Pharmacology, EarlyView.
This systematic review identified 112 population pharmacokinetic models of vancomycin in neonates and children. To support rational model selection for model‐informed precision, we developed and applied expert‐driven, transparent criteria that integrate both methodological rigour and clinical relevance.
Zoë Vander Elst, Pieter‐Jan Spiessens, Dorian Vanneste, Nada Dia, Matthias Gijsen, Isabel Spriet, Karel Allegaert, Erwin Dreesen, Anne Smits   +8 more
wiley   +1 more source

Vancomycin-resistant enterococcal infections: epidemiology, clinical manifestations, and optimal management

, 2015
Tristan O’Driscoll,1 Christopher W Crank2 1Department of Pharmacy Practice, Chicago College of Pharmacy, Downers Grove, IL, USA; 2Pharmacy Services, Rush-Copley Medical Center, Aurora, IL, USA Abstract: Since its discovery in England and France in
O’Driscoll T, Crank CW
core  

Therapeutic drug monitoring of antimicrobials in a paediatric setting: A retrospective single‐centre study

British Journal of Clinical Pharmacology, EarlyView.
Aims Paediatric pharmacokinetics differ significantly from adults due to age‐related physiological changes, necessitating precise dose adjustments. However, data on therapeutic drug monitoring (TDM) implementation in paediatric setting remain limited.
Gianluca Gazzaniga, Stefano Agliardi, Riccardo Giossi, Alice Schianchi, Alessandra Romandini, Thomas Virdis, Silvia Nerini Molteni, Maria Luisa De Angelis, Stefania Paccagnini, Cecilia Gechtman, Alice Proto, Marco Fossati, Silvia Oliveri, Giulia Angela Pattarino, Elena Altieri, Agnese Graziosi, Arianna Pani, Romano Danesi, Stefano Martinelli, Costantino De Giacomo, Francesco Scaglione   +20 more
wiley   +1 more source