Results 111 to 120 of about 302,754 (340)

Beyond PEGylation: Archaeal Lipids for Long‐Circulating Liposomes

open access: yesAdvanced NanoBiomed Research, EarlyView.
Archaeal lipid‐based liposomes, particularly those containing caldarchaeol (GDGT), were found to significantly prolong the circulation time of vancomycin in rats, matching the pharmacokinetic properties of PEGylated systems. These findings suggest archaeal lipids as promising non‐PEG excipients for parenteral applications to minimize drug clearance ...
Viktor Sedlmayr   +9 more
wiley   +1 more source

Prospective evaluation of vancomycin therapeutic usage and trough levels monitoring

open access: yesJournal of Infection in Developing Countries, 2018
Introduction: Vancomycin is the cornerstone of parenteral therapy for serious methicillin resistant Staphylococcus aureus infections. Optimal dosing of vancomycin is patient specific due to its narrow therapeutic window.
Wissam K Kabbara   +2 more
doaj   +1 more source

Short- and long-term effects of oral vancomycin on the human intestinal microbiota

open access: yesJournal of Antimicrobial Chemotherapy, 2016
Background Oral vancomycin remains the mainstay of therapy for severe infections produced by Clostridium difficile, the most prevalent cause of healthcare-associated infectious diarrhoea in developed countries.
Sandrine Isaac   +7 more
semanticscholar   +1 more source

Injectable Bone Cements: A Generational Framework for Bioactivity, Porosity, and Mechanobiological Design at the Nanoscale

open access: yesAdvanced NanoBiomed Research, EarlyView.
Key demographic, biological, and material considerations that drive the need for advanced injectable bone cement technologies. Injectable bone cements (IBCs) are widely used in orthopaedic and craniofacial applications due to their minimally invasive delivery and ability to provide early mechanical stabilisation.
Frank Fei   +2 more
wiley   +1 more source

Vancomycin-Associated Cast Nephropathy.

open access: yesJournal of the American Society of Nephrology, 2017
Vancomycin is a widely prescribed antibiotic, but the exact nature of vancomycin-associated nephrotoxicity is unclear, in particular when considering the frequent coadministration of aminoglycosides.
Y. Luque   +18 more
semanticscholar   +1 more source

Co‐Infection of Brucella canis and Brucella melitensis in a Domestic Dog With Zoonotic Transmission to Human, China

open access: yesAnimal Research and One Health, EarlyView.
Source attribution figure for human and dogs Brucella canis infections. ABSTRACT We report a rare occurrence of genetic material from both Brucella canis and B. melitensis detected in a domesticated dog from Jiangsu Province, China. The detection was confirmed through serological assays, quantitative PCR (qPCR), metagenomic and genomic sequencing ...
Shengxin Ge   +4 more
wiley   +1 more source

A new approach to Vancomycin utilization evaluation: A cross-sectional study in intensive care unit

open access: yesJournal of Research in Pharmacy Practice, 2016
Objective: The risk of methicillin-resistant Staphylococcus aureus infections in Intensive Care Unit (ICU) is increasing in recent years with high rate of morbidity and mortality.
Atefeh Mahmoodian   +2 more
doaj   +1 more source

Antimicrobial Susceptibility Trends Observed in Urinary Pathogens Obtained From New York State [PDF]

open access: yes, 2018
International guidelines recommend using local susceptibility data to direct empiric therapy for acute uncomplicated cystitis. We evaluated outpatient urinary isolate susceptibility trends in New York State.
Avery, Lisa M.   +10 more
core   +1 more source

Clinical microbiology study of diabetic foot ulcer in Iran; pathogens and antibacterial susceptibility [PDF]

open access: yes, 2012
The aim of this study was to investigate microbial pathogens and their antibiotic susceptibility profile in infected diabetic foot ulcers in Iranian patients.
Hayatshahi, A.   +5 more
core   +1 more source

Anterior Cruciate Ligament Reconstruction Using the Tape‐Active Reconstruction System With Semitendinosus Graft: A Primary Load‐Bearing Construct

open access: yesArthroscopy Techniques, EarlyView.
Abstract Anterior cruciate ligament reconstruction is a widely performed orthopaedic procedure; however, early graft elongation and loss of tension remain significant biomechanical challenges, particularly with the use of soft tissue autografts. In this technical note, the tape‐active reconstruction system is described as an augmentation technique in ...
Ahmet Emin Okutan, Lokman Kehribar
wiley   +1 more source

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