Results 151 to 160 of about 252,519 (340)

Failure of Once‐Daily Vancomycin for Staphylococcal Endocarditis [PDF]

, 1998
Paul E. Marik
openalex   +1 more source

TargetGen‐RNN model discovers novel antibiotic compound targeting drug‐resistant Staphylococcus aureus

Interdisciplinary Medicine, EarlyView.
TargetGen‐recurrent neural network (RNN), an advanced generative model, generated 28,708 unique and novel compounds, identifying SAK‐2970 as a potent antibiotic against drug‐resistant Staphylococcus aureus. Exhibiting strong biofilm inhibition, high therapeutic efficacy, and minimal systemic toxicity in vivo, SAK‐2970 highlights its safety and clinical
Shakeel Ahmad Khan, Adnan Shakoor, Sadia Kanwal   +2 more
wiley   +1 more source

Binding of a dimeric derivative of vancomycin with L-Lys-D-Ala-D-Lactate in solution and at surface: Insights into its enhanced activity against vancomycin-resistant bacteria.

, 1998
JH Rao, Lin Yan, Joydeep Lahiri, G. M. WHITESIDES, Sanchia Warren, RM Weis   +5 more
openalex   +1 more source

P99 Clinical validation of published vancomycin population PK models in critically ill neonates [PDF]

, 2019
Anouk van der Veen, RJ Keizer, Willem P. de Boode, Annemie Somers, Roger J. M. Brüggemann, Rob ter Heine, Pieter De Cock   +6 more
openalex   +1 more source

Frontiers in the Management of Orthopaedic Periprosthetic Joint Infection

Journal of Orthopaedic Research, EarlyView.
ABSTRACT Periprosthetic joint infection (PJI) is a devastating complication of total joint arthroplasty (TJA), one of the most frequently performed surgical procedures worldwide. Management of acute PJI commonly involves debridement, antibiotics, and implant retention (DAIR), though failure rates remain high due to antibiotic‐tolerant biofilms. Chronic
Michael F. Shannon, Victoria R. Wong, Samuelson E. Osifo, Timothy Edwards, Himanshu Rao, Jewelia Rempuszewski, Andrew J. Frear, Shaan Sadhwani, Neel B. Shah, Kenneth L. Urish   +9 more
wiley   +1 more source

Epicutaneo‐caval catheter occlusion in neonates without heparin infusion during parenteral nutrition: A descriptive cohort study

Journal of Parenteral and Enteral Nutrition, EarlyView.
Abstract Background Heparin is frequently infused in neonatal central venous catheters to prevent occlusion during parenteral nutrition despite limited evidence of its effectiveness and potential safety concerns in preterm infants. This study evaluated the incidence of catheter occlusion in epicutaneo‐caval catheters managed without heparin in a large ...
Vito D'Andrea, Giorgia Prontera, Cecilia Monachini, Micaela Cerreti, Francesca Baldo, Giovanni Barone, Giovanni Vento   +6 more
wiley   +1 more source

Ruxolitinib and vedolizumab salvage therapy in the setting of cytomegalovirus colitis for a patient with newly diagnosed very early onset inflammatory bowel disease

JPGN Reports, EarlyView.
Abstract Acute severe ulcerative colitis increases the risk for cytomegalovirus (CMV) infection, particularly with the use of immunocompromising medications. We report a case of a 4‐year‐old with newly diagnosed very early onset inflammatory bowel disease presenting with acute severe colitis refractory to both corticosteroids and infliximab, whose ...
Alison Laxer, Morris Edelman, Julie Gallagher, Benjamin Sahn   +3 more
wiley   +1 more source

Atypical Wounds in Chronic Graft‐Versus‐Host Disease and Peripheral Arterial Disease Caused by Tyrosine Kinase Inhibitors

JEADV Clinical Practice, EarlyView.
ABSTRACT The term “atypical wounds” primarily refers to lesions with immunological or cancerous etiologies. However, these wounds can also be drug‐induced. We report about a 32‐year‐old man with a 6‐year history of chronic myelogenous leukemia (CML) and chronic graft‐versus‐host disease (cGvHD) following an HLA‐compatible allogeneic stem cell ...
E. K. Stuermer, K. Malik, C. Willers, M. Augustin   +3 more
wiley   +1 more source

Epidemiology and Prognosis of Coagulase-Negative Staphylococcal Endocarditis: Impact of Vancomycin Minimum Inhibitory Concentration

, 2015
Cristina García de la Mària, Carlos Cervera, Juan M. Pericàs, Ximena Castañeda, Yolanda Armero, Dolors Soy, Manel Almela, Salvador Pié i Ninot, Carlos Falces, Carlos A. Mestres, José M. Gatell, Asunción Moreno, Francesc Marco, José M. Miró   +13 more
openalex   +2 more sources

Vancomycin-Associated Leukocytoclastic Vasculitis [PDF]

, 2011
Makhawadee Pongruangporn, David J. Ritchie, Dongsi Lu, Jonas Marschall   +3 more
openalex   +1 more source