Genome sequencing analysis of Streptomyces coelicolor mutants that overcome the phosphate-depending vancomycin lethal effect [PDF]
, 2018 Background Glycopeptide antibiotics inhibit bacterial cell-wall synthesis, and are important for the treatment of infections caused by multi drug-resistant strains of enterococci, streptococci and staphylococci.
Santos Beneit, Fernando
core +1 more source
High sporulation and overexpression of virulence factors in biofilms and reduced susceptibility to vancomycin and linezolid in recurrent Clostridium [Clostridioides] difficile infection isolates [PDF]
, 2019 Clostridium [Clostridioides] difficile infection (CDI) is one of the leading causes of diarrhea associated with medical care worldwide, and up to 60% of patients with CDI can develop a recurrent infection (R-CDI). A multi-species microbiota biofilm model
Baines, Simon +9 more
core +2 more sources
Persistent systemic microbial translocation, inflammation, and intestinal damage during Clostridioides difficile infection [PDF]
, 2020 Background. Clostridioides difficile infection (CDI) might be complicated by the development of nosocomial bloodstream infection (n-BSI). Based on the hypothesis that alteration of the normal gut integrity is present during CDI, we evaluated markers of ...
Aversano, L. +13 more
core +1 more source
Differential Activity of the Combination of Vancomycin and Amikacin on Planktonic vs. Biofilm-Growing Staphylococcus aureus Bacteria in a Hollow Fiber Infection Model [PDF]
, 2018 Combining currently available antibiotics to optimize their use is a promising strategy to reduce treatment failures against biofilm-associated infections. Nevertheless, most assays of such combinations have been performed in vitro on planktonic bacteria
Adamis +56 more
core +3 more sources
Direct replacement of antibodies with molecularly imprinted polymer (MIP) nanoparticles in ELISA - development of a novel assay for vancomycin [PDF]
, 2013 A simple and straightforward technique for coating microplate wells with molecularly imprinted polymer nanoparticles (nanoMIPs) to develop ELISA type assays is presented here for the first time.
Caygill, J. S. +7 more
core +1 more source
Evaluation of a vancomycin dosing nomogram in obese patients weighing at least 100 kilograms.
Pharmacy Practice, 2018 Background: There remains variability in both practice and evidence related to optimal initial empiric dosing strategies for vancomycin. Objective: Our primary objective was to describe the percentage of obese patients receiving vancomycin doses ...
Bowers RD +5 more
doaj +1 more source
Frontiers in Pediatrics, 2022 ObjectiveTo explore the efficacy and safety of vancomycin as measured by pharmacokinetic/pharmacodynamic parameters in children with severe infection in the Pediatric Intensive Care Unit (PICU) and to determine the appropriate threshold for avoiding ...
Bo Zhou +28 more
doaj +1 more source
Frontiers in Pharmacology, 2022 Objective: The decision of vancomycin dosage for central nervous system (CNS) infections is still a challenge because its bactericidal nature in cerebrospinal fluid (CSF) has not been confirmed by human studies.
Shu-Ping Liu +10 more
doaj +1 more source
World Allergy Organization Journal, 2013 The prevalence of Clostridium difficile infection (CDI) is increasing worldwide. Oral vancomycin is an effective and frequently used treatment. However, patients with CDI who are allergic to intravenous vancomycin cannot receive oral vancomycin due to ...
Shanti Mahabir +4 more
doaj +1 more source
Vancomycin-resistantEnterococcus
Swiss Medical Weekly, 2012 The reported prevalence of vancomycin-resistant Enterococcus faecium (VRE) in Switzerland for the years 2008–2010 has been low at <5%. At the University Hospital Zurich, 17 cases of VRE were detected between 28 December 2009 and 15 February 2010. Nine cases were diagnosed clinically; eight cases were detected by rectal screening. The centre of
Thierfelder, C +6 more
openaire +4 more sources