Results 101 to 110 of about 3,124 (186)
Circ‐IGF1R inhibits cell invasion and migration in non‐small cell lung cancer
Thoracic Cancer, 2020 Background Circular RNA (circRNA) is a novel molecular marker and target candidate that is closely associated with tumor invasion and migration. The mechanism of action of hsa_circ_0005035 (circ‐IGF1R) in non‐small cell lung cancer remains unclear.
Zhanyu Xu +8 more
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eLife, 2019 The control of cell fate through oriented cell division is imperative for proper organ development. Basal epidermal progenitor cells divide parallel or perpendicular to the basement membrane to self-renew or produce differentiated stratified layers, but ...
Kimberly Box +2 more
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Vangl2 and Early Cardiac Development
, 2007 The establishment of polarity is a crucial event for creating asymmetry during development. Planar cell polarity (PCP) is essential for polarity within the plane of a tissue and is required for a number of developmental processes including gastrulation ...
Rhee, Hong Jun
core
Altered tooth morphogenesis after silencing the planar cell polarity core component, Vangl2
, 2017 Vangl2, one of the core components of the planar cell polarity (PCP) pathway, has an important role in the regulation of morphogenesis in several tissues.
정한성, 그린 데이비드
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Biology Open, 2017 Cell polarity has a fundamental role in shaping the morphology of cells and growing tissues. Polarity is commonly thought to be established in response to extracellular signals.
Artal Moreno-Fortuny +3 more
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Vangl2 is expressed in the distal outflow region.
, 2014 A) Cartoon showing the region encompassing the dorsal pericardial wall and the distal outflow tract, including the region we describe as the transition zone.
Simon A. Ramsbottom (676880) +8 more
core +1 more source
Regulation of Planar Cell Polarity and Vangl2 Trafficking by Tmem14a [PDF]
, 2012 Planar cell polarity (PCP) refers to the coordinated orientation, movement, or structure of cells within the plane of a tissue. Zebrafish PCP mutants such as the vangl2 mutant exhibit defects in convergent extension, neural tube morphogenesis, and ...
Chea, Evelyn
core +2 more sources
Nature Communications, 2016 Defects in non-canonical Wnt/planar cell polarity signalling have recently been linked to breast cancer aggressiveness. Puvirajesinghe et al. identify VANGL2, p62/SQSTM1 and JNK as important players in this pathway which may be amenable to therapeutic ...
Tania M. Puvirajesinghe +21 more
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The loop-tail mouse model displays open and closed caudal neural tube defects
Disease Models & Mechanisms, 2023 Beatriz Fernández-Santos +7 more
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353 Eph/Ephrin Signaling Influences Innervation of Outer Hair Cells in Cochlea
Journal of Clinical and Translational ScienceOBJECTIVES/GOALS: 48,000,000 people in the U.S. have hearing loss, negatively impacting quality of life and work. Unveiling axon guidance for auditory type II spiral ganglia neurons (SGNs) will aid development of new therapies.
Deborah Jane George +4 more
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